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Protein Overview: polh-1

General Information:
Name(s) found: polh-1 / CE40206 [WormBase]
Description(s) found:
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  • WBGene00018721 locus:polh-1 status:Confirmed UniProt:G5EFY1 protein_id:CCD62153.1 [WormBase]
  • gi|92110137|gb|AAB70988.5| Polh (dna polymerase eta) homolog protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|84570637|dbj|BAE72703.1| DNA polymerase eta [Caenorhabditis elegans] [NCBI NR]
  • gi|115534089|ref|NP_497480.2| POLH (DNA polymerase eta) homolog family member (polh-1) [Caenorhabditis elegans] [NCBI NR]
  • CE40206 WBGene00018721 locus:polh-1 status:Confirmed UniProt:O17219_CAEEL protein_id:AAB70988.5 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE40206 WBGene00018721 locus:polh-1 status:Confirmed UniProt:O17219_CAEEL protein_id:AAB70988.5| [wormORF-contam.fasta]
  • CE40206 WBGene00018721 locus:polh-1 status:Confirmed TR:O17219 protein_id:AAB70988.5 [wormpep160-contam.fasta]
  • POLH (DNA polymerase eta) homolog family member (polh-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Polh (dna polymerase eta) homolog protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • DNA polymerase eta [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE40206 WBGene00018721 locus:polh-1 status:Confirmed UniProt:O17219 protein_id:AAB70988.5 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE40206 WBGene00018721 locus:polh-1 status:Confirmed UniProt:G5EFY1 protein_id:CCD62153.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • DNA polymerase eta OS=Caenorhabditis elegans GN=polh-1 PE=2 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 584 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: DNA repair [IEALink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [IEALink to PubMed article]
    damaged DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRVISLIDM DCFYAQVEQR DNPSLWGQPV IVVQHSRQGI EGGILAVSYE ARPFGVKRGM  60
   61 TVAEAKLKCP QISICHVPIG EYVDKADIQK YRDASAEVFR VLNNYDSQII IEKASVDEAF 120
  121 LDLSAYTNQK LQELRENEGL EEFLQAAITY LPTTHLATGE DVKENEHLRE DVLLEYIENA 180
  181 RNCTENLLLL IAAVTVEQIR QQIHEETQFF CSAGVGNNKM MAKLVCARHK PRQQTLIPWF 240
  241 YVREILRLTP IGDVRGFGGK MGNRIQEMLN ITLMGELLEV DISQLIETFP NQHEYLRSVA 300
  301 EGHCDEPVRP RKESSSIAVS KNFPGKLSIR SVLELKKWLD GLTKELAKRL ATDQAENKRT 360
  361 AENLVYSLLT EDGKPQKTLK ITSYHPDTLF EQIWAAMKGL NKTNATKNED SGPWTPPILN 420
  421 ISLSATRFQP GIPAQNRSIH EWLYEKKTRK SRRKAAIYDE NDGREDVIFV EPPEKLKKPN 480
  481 PTPKSTGTDG DFIVLGSDSD DDVVQPKTDD NWIFVDGKKF SKMAWRHLPP DIKKHYQHRI 540
  541 ALEEARALKS KTGGSRKRAG AHTDNAQKPK KPKSLESFFK KKKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..437] PSI-BLAST 81.39794 No description for 2oh2A was found.
    2 View Details [438..498] MSA 3.451996 View MSA. No confident structure predictions are available.
    3 View Details [499..584] MSA 1.137996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle