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Protein Overview: ABL2_MOUSE

General Information:
Name(s) found: ABL2_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|68534947|ref|NP_033725.1| v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) [Mus musculus] [NCBI NR]
  • gi|68139002|gb|AAY86039.1| ABL2 [Mus musculus] [NCBI NR]
  • gi|118582158|sp|Q4JIM5.1|ABL2_MOUSE RecName: Full=Tyrosine-protein kinase ABL2; AltName: Full=Abelson murine leukemia viral oncogene homolog 2; AltName: Full=Abelson-related gene protein; AltName: Full=Tyrosine kinase ARG [NCBI NR]
  • Abelson tyrosine-protein kinase 2 OS=Mus musculus GN=Abl2 PE=1 SV=1 [Swiss-Prot]
  • Tax_Id=10090 ABL2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Tyrosine-protein kinase ABL2 (Abelson murine leukemia viral oncogene homolog 2) (Abelson-related gene protein) (Tyrosine kinase ARG) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • ABL2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Abl2 Tyrosine-protein kinase ABL2 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Abl2 Tyrosine-protein kinase ABL2 ENSMUSG00000026596 IPI00117039 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00117039.6|SWISS-PROT:Q4JIM5|ENSEMBL:ENSMUSP00000027888|REFSEQ:NP_033725 Tax_Id=10090 Gene_Symbol=Abl2 Tyrosine-protein kinase ABL2 [ipi.MOUSE.fasta.20090209]
  • Tyrosine-protein kinase ABL2 OS=Mus musculus GN=Abl2 [011711_HMR.fasta]
  • Tyrosine-protein kinase ABL2 OS=Mus musculus GN=Abl2 PE=1 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Abl2 Abelson tyrosine-protein kinase 2 [EBI_IPI_mouse_V3_87_09-27-2011_reversed.fasta]
  • sp|Q4JIM5|ABL2_MOUSE Abelson tyrosine-protein kinase 2 OS=Mus musculus GN=Abl2 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 1182 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    cytoplasm [IEA]
    actin cytoskeleton [IDA]
    cytoplasmic membrane-bounded vesicle [TAS]
    Biological Process: peptidyl-tyrosine phosphorylation [IDA]
    signal transduction [IEA]
    actin filament organization [IDA]
    auxin biosynthetic process [IEA]
    cell adhesion [IEA]
    protein amino acid phosphorylation [IDA]
    actin cytoskeleton organization [IDA]
    actin filament bundle assembly [IDA]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [IDA]
    ATP binding [IEA]
    protein tyrosine kinase activity [IDA]
    protein binding [IEA]
    non-membrane spanning protein tyrosine kinase activity [IEA]
    metal ion binding [IEA]
    manganese ion binding [IDA]
    protein kinase activity [IEA]
    transferase activity [IEA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQVGRVGE APGLQQPQPR GIRGSSAARP SGRRRDPAGR TADAGFNVFT QHDHFASCVE  60
   61 DGFEGDKTGG SSPEVLHRPF GCDAESQALN EAIRWSSKEN LLGATESDPN LFVALYDFVA 120
  121 SGDNTLSITK GEKLRVLGYN QNGEWSEVRS KNGQGWVPSN YITPVNSLEK HSWYHGPVSR 180
  181 SAAEYLLSSL INGSFLVRES ESSPGQLSIS LRYEGRVYHY RINTTTDSKV YVTAESRFST 240
  241 LAELVHHHST VADGLVTTLH YPAPKCNKPT VYGVSPIHDK WEMERTDITM KHKLGGGQYG 300
  301 EVYVGVWKKY SLTVAVKTFK EDTMEVEEFL KEAAVMKEIK HPNLVQLLGV CTLEPPFYIV 360
  361 TEYMPYGNLL DYLRECSREE VTAVVLLYMA TQISSAMEYL EKKNFIHRDL AARNCLVGEN 420
  421 HVVKVADFGL SRLMTGDTYT AHAGAKFPIK WTAPESLAYN TFSIKSDVWA FGVLLWEIAT 480
  481 YGMSPYPGID LSQVYDLLEK GYRMEQPEGC PPKVYELMRA CWKWSPADRP SFAETHQAFE 540
  541 TMFHDSSISE EVAEELGRTA SSSSVVPYLP RLPLLPSKTR TLRKQGENKE NLDGGLDAAE 600
  601 SLASSSAPAG FIRSTQASSG SPALPRKQRD KSPSSLLEDA KETCFTRDRK GGFFSSFMKK 660
  661 RNAPTPPKRS SSFREMENQP HKKYELTGNF SPVASLQNAD GFSVAPSQQE PNLVPAKCYG 720
  721 GSFAQRNLCA DDDSGGGGGS GTAGGGWSGI TGFFTPRLIK KTLGLRAGKP TASDDTSKPF 780
  781 PRSNSTSSMS SGLPEQDRMA MTLPRNCQRS KLQLERTVST SSQPEENVDR ANDMLPKKSE 840
  841 EGAAPARERP KAKLLPRGAT ALPLRAPDPA ITESDSPGVG VAGVAAAPKG KERNGGTRLG 900
  901 VAGVPEDGEQ LGWSSPAKAV AVLPTTHNHK VPVLISPTLK HTPADVQLIG TDSQGNKFKL 960
  961 LSEHQVTSSG DKDRPRRVKP KCAPPPPPVM RLLQHPSTCS DPEEEPTAPP AGQHTPETQE1020
 1021 GGKKAAPGPV PSSGKPGRPV MPPPQVPLPT SSISPAKMAN GTAGTKVALR KTKQAAEKIS1080
 1081 ADKISKEALL ECADLLSSAI TEPVPNSQLV DTGHQLLDYC SGYVDSIPQT RNKFAFREAV1140
 1141 SKLELSLQEL QVSSTAAGVP GTNPVLNNLL SCVQEISDVV QR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle