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Protein Overview: SIFR-PB

General Information:
Name(s) found: SIFR-PB / FBpp0083498 [FlyBase]
Description(s) found:
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  • gi|78711850|ref|NP_732614.2| SIFamide receptor, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|71854575|gb|AAF55878.2| SIFamide receptor, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene SIFamide receptor is referred to in FlyBase by the symbol Dmel\SIFR (CG10823, FBgn0038880). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17102386..17119720. It has the cytological map location 93D2-93D4. Based on sequence similarity, it is predicted to have molecular function</span>: G-protein coupled receptor activity; neuropeptide receptor activity; peptide receptor activity, G-protein coupled. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:complement(17105674..17106328,17109800..17109899,17116894..17116960,17117041..17117790); ID=FBpp0083498; name=SIFR-PB; parent=FBgn0038880,FBtr0084099; dbxref=GB_protein:AAF55878.1,FlyBase_Annotation_IDs:CG10823-PB,FlyBase:FBpp0083498, [fly-100309-contam.fasta]
  • SIFamide receptor CG10823-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG10823-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(17105674..17106328,17109800..17109899,17116894..17116960,17117041..17117790); ID=FBpp0083498; name=SIFR-PB; parent=FBgn0038880,FBtr0084099; dbxref=GB_protein:AAF55878.1,FlyBase_Annotation_IDs:CG10823-PB,FlyBase:FBpp0083498,GB_protein:AAF55878.2,REFSEQ:NP_732614,GB_protein:AAF55878; MD5=3d00cb6b882011a119ccdfcf2b3946b2; length=523; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(17105674..17106328,17109800..17109899,17116894..17116960,17117041..17117790); ID=FBpp0083498; name=SIFR-PB; parent=FBgn0038880,FBtr0084099; dbxref=GB_protein:AAF55878.1,FlyBase_Annotation_IDs:CG10823-PB,FlyBase:FBpp0083498,GB_protein:AAF55878.2,REFSEQ:NP_732614,GB_protein:AAF55878; MD5=3d00cb6b882011a119ccdfcf2b3946b2; length=523; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • SIFamide receptor, isoform B OS=Drosophila melanogaster GN=SIFR PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(17105674..17106328,17109800..17109899,17116894..17116960,17117041..17117790); ID=FBpp0083498; name=SIFR-PB; parent=FBgn0038880,FBtr0084099; dbxref=GB_protein:AAF55878.1,FlyBase_Annotation_IDs:CG10823-PB,FlyBase:FBpp0083498,GB_protein:AAF55878.2,REFSEQ:NP_732614,GB_protein:AAF55878,FlyMine:FBpp0083498,modMine:FBpp0083498; MD5=3d00cb6b882011a119ccdfcf2b3946b2; length=523; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
    • Organism: Drosophila melanogaster
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA][ISS]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEA][ISS]
    Molecular Function: G-protein coupled receptor activity [ISS]
    peptide receptor activity, G-protein coupled [ISS]
    neuropeptide receptor activity [ISS]
    neuropeptide Y receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMAASGRIRK RKHKSHTSGD VPSTTTSVPM PIPTMAPGKM VAETMEEAAA LAGDYNNFTH  60
   61 NFVDLQNLLS FNELNGTSGS GGTAVSSLGS SSAIKLNNSA ITDTLLGTVL TTATATVAPA 120
  121 ASSLLATLAA TTTASARGSL AGKSLAIADA TSSTYYSNLL NLSPATTSLI SAAAATKSYN 180
  181 DSALRWEQLD GSVDFGFDPL YRHSLAMSMV YCVAYIVVFL VGLIGNSFVI AVVLRAPRMR 240
  241 TVTNYFIVNL AIADILVIVF CLPATLIGNI FVPWMLGWLM CKFVPYIQGV SVAASVYSLI 300
  301 AVSLDRFIAI WWPLKQMTKR RARIMIIGIW VIALVTTIPW LLFFDLVPAE EVFSDALVSA 360
  361 YSQPQFLCQE VWPPGTDGNL YFLLANLVAC YLLPMSLITL CYVLIWIKVS TRSIPGESKD 420
  421 AQMDRMQQKS KVKVIKMLVA VVILFVLSWL PLYVIFARIK FGSDISQEEF EILKKVMPVA 480
  481 QWLGSSNSCI NPILYSVNKK YRRGFAAIIK SRSCCGRLRL VNF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] deduced N/A No confident structure predictions are available.
    2 View Details [184..523] PSI-BLAST 41.154902 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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