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Protein Overview: gish-PG

General Information:
Name(s) found: gish-PG / FBpp0099737 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • The gene gilgamesh is referred to in FlyBase by the symbol Dmel\gish (CG6963, FBgn0250823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12098176..12128094. It has the cytological map location 89B9-89B12. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: glial cell migration; protein amino acid phosphorylation; Wnt receptor signaling pathway; spermatogenesis. 48 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; eye; photoreceptor cell; ommatidium. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: spermatogenesis [IMP]
    Wnt receptor signaling pathway [IMP]
    protein amino acid phosphorylation [IDA][NAS]
    glial cell migration [IMP]
    Molecular Function: ATP binding [IEA]
    protein serine/threonine kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRKYLYIQK TNIKEENGGG PQTTTAGPSA GNVANATTAL AGGKSSSNNM YSTRQSVSTT  60
   61 TGVLMVGPNF RVGKKIGCGN FGELRLGKNL YNNEHVAIKM EPMKSKAPQL HLEYRFYKLL 120
  121 GSHADNAPDG IPRIYHLGTC GGRYNAMVLE LLGLSLEDLF NICARKFSLK TVLMIAKQLL 180
  181 HRIEYVHSRH LIYRDVKPEN FLIGRTSTKR EKIIHIIDFG LAKEYIDLDT NRHIPYREHK 240
  241 SLTGTARYMS INTHMGREQS RRDDLEALGH MFMYFLRGSL PWQGLKADTL KERYQKIGDT 300
  301 KRATPIEVLC DGHPEEFATY LRYVRRLDFF ETPDYDFLRR LFQDLFDRKG YTDEGEFDWT 360
  361 GKTMSTPVGS LQTGHEVIIS PNKDRHNVTA KTNAKGGVAA WPDVPKPGAT LGNLTPADRH 420
  421 GSVQVVSSTN GELNPDDPTA GHSNTPITQQ PEVEVVDETK CCCFFKRKKK KSTRQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..420] PSI-BLAST 59.0 No description for 2chlA was found.
    2 View Details [421..476] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle