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Protein Overview: SPEG_RAT

General Information:
Name(s) found: SPEG_RAT [Swiss-Prot]
Description(s) found:
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  • gi|97537204|sp|Q63638.2|SPEG_RAT RecName: Full=Striated muscle-specific serine/threonine-protein kinase; AltName: Full=Aortic preferentially expressed protein 1; AltName: Full=APEG-1 [NCBI NR]
  • gi|62655241|ref|XP_343597.2| PREDICTED: similar to aortic preferentially expressed gene 1 [Rattus norvegicus] [NCBI NR]
  • gi|157818307|ref|NP_001102272.1| SPEG complex locus [Rattus norvegicus] [NCBI NR]
  • gi|149016190|gb|EDL75436.1| similar to aortic preferentially expressed gene 1, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|109487359|ref|XP_001058207.1| PREDICTED: similar to aortic preferentially expressed gene 1 [Rattus norvegicus] [NCBI NR]
  • Striated muscle-specific serine/threonine-protein kinase OS=Rattus norvegicus GN=Speg PE=1 SV=2 [Swiss-Prot]
  • Tax_Id=10116 Splice Isoform 1 of Striated muscle-specific serine/threonine protein kinase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 PREDICTED: similar to striated muscle-specific serine/threonine protein kinase [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta]
  • Striated muscle-specific serine/threonine protein kinase (Aortic preferentially expressed protein 1) (APEG-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • hypothetical protein LOC363256 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • similar to aortic preferentially expressed gene 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • SPEG complex locus [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • PREDICTED: similar to aortic preferentially expressed gene 1 [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Speg Isoform 1 of Striated muscle-specific serine/threonine-protein kinase [rat-ipi-250309-contam.fasta]
  • Isoform 1 of Striated muscle-specific serine/threonine-protein kinase OS=Rattus norvegicus GN=Speg [011711_HMR.fasta]
  • Striated muscle-specific serine/threonine-protein kinase OS=Rattus norvegicus GN=Speg PE=2 SV=2 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 3259 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IMP]
    Biological Process: muscle cell differentiation [IEP]
    protein amino acid phosphorylation [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein serine/threonine kinase activity [IEA]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKARGTRGE DAGTRAPPSP GVPPKRAKVG AGRGVLVTGA GAGAPVFLRP LKNAAVCAGS  60
   61 DVRLRVVVSG TPEPSLSWFR DGQLLPTPVP EPSCLWLRNC GAQDAGVYSC SAQNERGKAS 120
  121 CEAVLTVLEV RDSETAEDDI SDVPGTQRLE LRDDRAFSTP TGGSDTLVGT SLDTPPTSVT 180
  181 GTSEEQVSWW GSGQTVLEQE AGSGGGTRPL PGSPRQAQTT GAGPRHLGVE PLVRASRANL 240
  241 VGASWGSEDS LSVASDLYGS AFSLYRGRAL SIHVSIPPSG LRREEPDLQP QPASDALRPR 300
  301 PALPPPSKSA LLPPPSPRVG KRALPGSSAQ PPATPTSPHR CTQEPSLPED ITTTEEKRGK 360
  361 KPKSSGPSLA GTVESRPQTP LSEASGRLSA LGRSPRLVRA GSRILDKLQF FEERRRSLER 420
  421 SDSPPAPLRP WVPLRKARSL EQPKSEGGAA WDTPGASQEE LRSPRGSVAE RRRLFQQKAA 480
  481 SLDERTRQRS ATSDLELRFA QELGRIRRST SREELVRSHE SLRATLQRAP SPREPGEPPL 540
  541 FSRPSIPKTS RAVSPAATQP PPPSGAGKSG DETGRPRSRG PVGRTEPGEG PQQEIKRRDQ 600
  601 FPLTRSRAIQ ECRSPVPPFT ADPPESRTKA PSARKREPPA QAVRFLPWAT PGVEDSVLPQ 660
  661 TLEKNRAGPE AEKRLRRGPE EDGPWGAWDR RGTRSQGKGR RARPTSPELE SSDDSYVSAG 720
  721 EEPLEAPVFE IPLQNMVVAP GADVLLKCII TANPPPQVSW KKDGSVLHSE GRLLIRAEGE 780
  781 RHTLLLREAQ AADAGSYTAT ATNELGQASC ASSLAVRPGA STSPFSSPIT SDEEYLSPPE 840
  841 EFPEPGETWS RTPTMKPSPS QDRDSSDSSS KAPPTFKVSL MDQSVREGQD VIMSIRVQGE 900
  901 PKPVVSWLRN RQPVRPDQRR FAEEAEGGLC RLRILAAERG DAGFYTCKAV NEYGARQCEA 960
  961 RLEVRAHPES RSLAVLAPLQ DVDVGAGEMA LFECLVAGPA DVEVDWLCRG RLLQPALLKC1020
 1021 KMHFDGRKCK LLLTSVHEDD SGVYTCKLST VKDELTCSAR LTVRPSLAPL FTRLLEDVEV1080
 1081 LEGRAARLDC KISGTPPPSV TWTHFGHPVN ESENLRLRQD GGLHSLHIAR VGSEDEGLYE1140
 1141 VSATNTHGQA HCSAQLYVEE PRTAASGPSS KLEKMPSIPE EPEHGDLERL SIPDFLRPLQ1200
 1201 DLEVGLAKEA MLECQVTGLP YPTISWFHNG HRIQSSDDRR MTQYRDIHRL VFPAVGPQHA1260
 1261 GVYKSVIANK LGKAACYAHL YVTDVVPGPP DGAPQVVAVT GRMVTLSWNP PRSLDMAIDP1320
 1321 DSLTYTVQHQ VLGSDQWTAL VTGLREPEWA ATGLKKGLHH IFRVLSSSGK SSSKPSAPSE1380
 1381 PVQLLEHGPP LEEAPAVLDK QDIVYVVEGQ PACVTVTFNH VEAQVVWRSC RGALLEPRTG1440
 1441 VYELSQPDDD QYCLRICRVS RRDLGPLTCS ARNRHGTKAC SITLELAEAP RFESIMEDVE1500
 1501 VGPGETARFA VVVEGKPLPD IMWYKDEVLL AESNHVSFVY EENECSLVVL SAGSQDGGVY1560
 1561 TCTARNLAGE VSCKAELSVH SAQTAMEVEG VGEDEEHRGR RLSDYYDIHQ EIGRGAFSYL1620
 1621 RRVVERSSGL EFAAKFIPSQ AKPKASARRE ARLLARLQHD CVLYFHEAFE RRRGLVIVTE1680
 1681 LCTEELLERM ARKPTVCESE TRTYMRQVLE GIGYLHQSHV LHLDVKPENL LVWDGAGGEE1740
 1741 QVRICDFGNA QELTPGEPQY CQFGTPEFVA PEIVNQSPVS GVTDIWPVGV VAFLCLTGIS1800
 1801 PFVGENDRTT LMNIRNYNVA FEETTFLSLS REARGFLIKV LVQDRLRPTA EETLEHPWFK1860
 1861 TEAKGAEVST DHLKLFLSRR RWQRSQISYK CHLVLRPIPE LLRAPPERVW VAMPRRQPPS1920
 1921 GGLSSSSDSE EEELEELPSV PRPLQPEFSG SRVSLTDIPT EDEALGTPEA GAATPMDWQE1980
 1981 QGRAPSKDQE APSPEALPSP GQESPDGPSP RRPELRRGSS AESALPRVGS REPGRSLHKA2040
 2041 ASVELPQRRS PSPGATRLTR GGLGEGEYAQ RLQALRQRLL RGGPEDGKVS GLRGPLLESL2100
 2101 GGRARDPRMA RAASSEAAPH HQPPPESRGL QKSSSFSQGE AEPRGRHRRA GAPLEIPVAR2160
 2161 LGARRLQESP SLSALSETQP PSPALPSAPK PSITKSPEPS AATSRDSPQP PAPQPVPEKI2220
 2221 PEPKPEPVRA AKPAQPPLAL QMPAQSLTPY AQIMQSLQLS SPTLSPQVPP SEPKPHAAVF2280
 2281 ARVASPPPGA SEKRVPSARI PPVLAEKVRV PTVPPRPGSS LSGSIENLES EAVFEAKFKR2340
 2341 SRESPLSRGL RLLSRSRSEE RGPFRGAEDD GIYRPSPAGT PLELVRRPER SRSVQDLRVA2400
 2401 GEPGLVRRLS LSLSQKLRRT PPGQRHPAWE SRSGDGESSE GGSSARGSPV LAVRRRLSST2460
 2461 LERLSSRLQR SGSSEDSGGA SGRSTPLFGR LRRATSEGES LRRLGVPHNQ LASQTGATTP2520
 2521 SAESLGSEAS GTSGSSAPGE SRSRHRWGLS RLRKDKGLSQ PNLSASVQED LGHQYVPSES2580
 2581 DFPPVFHIKL KDQVLLEGEA ATLLCLPAAC PTPRISWMKD KQSLRSEPSV VIVSCKDGRQ2640
 2641 LLSIPRASKR HAGLYECSAT NVLGSITSSC TVAVARTPGK LAPPEVPQTY CDTALVLWKP2700
 2701 GDSRAPCTYT LERRVDGESV WHPVSSGIPD CYYNVTQLPV GVTVRFRVAC SNRAGQGPFS2760
 2761 NPSEKVFIRG TQDSPAQSAA APRDAPVTSG PTRAPPPDSP TSLVPTPPLA PQVSQASTLS2820
 2821 PSTSSMSANQ ALSSLKAVGP PPATPPRKHR GLLATQQAEP SPPSILVTPS EHKSFVPDTG2880
 2881 TLTPTSSPQG VKPAPSSSSL YMVTSFVSAP PDPQPPAPEP PPEPTKVTVR SLSPAKEVVS2940
 2941 SPTPESTTLR QGPPQKPYTF LEEKARGRFG VVRSCRENAT GRTFVAKIVP YAAEGKRRVL3000
 3001 QEYEVLRTLH HERLMSLHEA YITPRYLVLI AESCGNRELL CGLSDRFRYS EDDVATYVVQ3060
 3061 LLQGLDYLHG RHVLHLDIKP DNLLLAADNA LKIVDFGSAQ PYNPQALKPL GHRTGTLEFM3120
 3121 APEMVRGDPI GSATDIWGAG VLTYIMLSGY SPFYEPDPQE TEARIVGGRF DAFQLYPNTS3180
 3181 QSATLFLRKV LSVHPWSRPS LQDCLAHPWL QDAYLMKLRR QTLTFTTNRL KEFLGEQRRR3240
 3241 RAEAATRHKV LLRSYPGSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle