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Protein Overview: dcap-2

General Information:
Name(s) found: dcap-2 / CE39374 [WormBase]
Description(s) found:
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  • WBGene00003582 locus:dcap-2 mRNA-decapping enzyme 2 status:Partially_confirmed UniProt:O62255 protein_id:CAB05204.2 [WormBase]
  • gi|82658170|emb|CAB05204.2| C. elegans protein F52G2.1b, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|82657828|emb|CAJ43919.1| C. elegans protein F52G2.1b, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|205371800|sp|O62255.4|DCP2_CAEEL RecName: Full=mRNA-decapping enzyme 2; AltName: Full=Nudix hydrolase 5 [NCBI NR]
  • gi|115534462|ref|NP_502609.2| mRNA DeCAPping enzyme family member (dcap-2) [Caenorhabditis elegans] [NCBI NR]
  • mRNA-decapping enzyme 2 OS=Caenorhabditis elegans GN=dcap-2 PE=2 SV=4 [Swiss-Prot]
  • CE39374 WBGene00003582 locus:dcap-2 Bacterial mutT protein status:Partially_confirmed UniProt:O62255 protein_id:CAJ43919.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE39374 WBGene00003582 locus:dcap-2 Bacterial mutT protein status:Partially_confirmed UniProt:O62255 protein_id:CAJ43919.1| [wormORF-contam.fasta]
  • CE39374 WBGene00003582 locus:dcap-2 Bacterial mutT protein status:Partially_confirmed SW:O62255 protein_id:CAJ43919.1 [wormpep160-contam.fasta]
  • mRNA DeCAPping enzyme family member (dcap-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F52G2.1b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE39374 WBGene00003582 locus:dcap-2 Bacterial mutT protein status:Partially_confirmed UniProt:O62255 protein_id:CAB05204.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE39374 WBGene00003582 locus:dcap-2 status:Partially_confirmed UniProt:O62255 protein_id:CAB05204.2 mRNA-decapping enzyme 2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 786 amino acids

    Gene Ontology:
    Cellular Component: P granule [IDALink to PubMed article]
    cytoplasmic mRNA processing body [IDALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMP]
    Molecular Function: hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEISTENWCK KPKNRSIFSK NISFQKQNKS TEEPPSSVQK LLASLQQAQN KSDLSEQPST  60
   61 SKPKKNEKRK KAVAQAPASA PAPGPEEKKK QPKRASVGAR MQQQAENARI SQTKRPRQVS 120
  121 TSKGSSRNTT APEQQNYQQQ QQQYKGPRIP TDILDELEFR FISNMVECEI NDNIRVCFHL 180
  181 ELAHWYYIDH MVEDDKISGC PNVGSRDFNF QMCQHCRVLR KYAHRADEVL AKFREYKSTV 240
  241 PTYGAILVDP EMDHVVLVQS YFAKGKNWGF PKGKINQAEP PRDAAIRETF EETGFDFGIY 300
  301 SEKEKKFQRF INDGMVRLYL VKNVPKDFNF QPQTRKEIRK IEWFKIDDLP TDKTDELPAY 360
  361 LQGNKFYMVM PFVKDIQIYV QKEKEKLRRR KAEAVQSTPS SSIFSQLFPA QPPPPVPEDA 420
  421 TPTRPMYKRL TSEELFSAFK NPPAGEVARP TLPDMSPAVN GLDTLAVLGI CTPLKPGASL 480
  481 NEFSGAPQNC PMISEEAGSP ADPSAEIGFA MPMDLKQPVV TSDHPWQHHK ISDSSAPPQT 540
  541 LESHQGWLDT QLVNTIMHSP NHPLPPTSNS PATPTAVLGH LIGKPIQPQA ILPQAATPTA 600
  601 LGSAEKPKSS RISLSDNSAF KAISSTQKQS IPKATAAPPS TEKTRSASLS GSSQVVGKPA 660
  661 RNLFNSVVSP VSSGIQSIQG DGGAWEDVWF REQLAATTTA GTSISSLAAS NQELAMINRE 720
  721 ETPIEDPYFK QQAYQKAQKA QSLIPACSQW TNSIKLDIDY VVGPLSFWMQ QFSTKSPVSG 780
  781 TGPQLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] deduced N/A No confident structure predictions are available.
    2 View Details [130..395] PSI-BLAST 89.0 Crystal structure of S.pombe mRNA decapping enzyme Dcp2p
    3 View Details [396..455] PSI-BLAST 11.39794 RBP1
    4 View Details [456..625] deduced N/A No confident structure predictions are available.
    5 View Details [626..786] MSA 3.270995 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle