Protein Overview: TET2_MOUSE

General Information:
Name(s) found:	TET2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|82891723\|ref\|XP_485314.3\| PREDICTED: hypothetical protein LOC214133 isoform 1 [Mus musculus] [NCBI NR] gi\|239938840\|sp\|Q4JK59.3\|TET2_MOUSE RecName: Full=Probable methylcytosine dioxygenase TET2; AltName: Full=Protein Ayu17-449 [NCBI NR] gi\|157057152\|ref\|NP_001035490.2\| tet oncogene family member 2 [Mus musculus] [NCBI NR] Methylcytosine dioxygenase TET2 OS=Mus musculus GN=Tet2 PE=1 SV=3 [Swiss-Prot] PREDICTED: hypothetical protein LOC214133 isoform 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] tet oncogene family member 2 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] probable methylcytosine dioxygenase TET2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] Isoform 1 of Probable methylcytosine dioxygenase TET2 OS=Mus musculus GN=Tet2 [011711_HMR.fasta] Probable methylcytosine dioxygenase TET2 OS=Mus musculus GN=Tet2 PE=2 SV=3 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] Isoform 1 of Methylcytosine dioxygenase TET2 OS=Mus musculus GN=Tet2 [122011_mus.fasta] Tax_Id=10090 Gene_Symbol=Tet2 Isoform 1 of Methylcytosine dioxygenase TET2 [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|Q4JK59\|TET2_MOUSE Methylcytosine dioxygenase TET2 OS=Mus musculus GN=Tet2 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1912 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	kidney development [IMP] post-embryonic development [IMP] oxidation reduction [IEA] cell cycle [IEA]
Molecular Function:	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] metal ion binding [IEA] oxidoreductase activity [IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQDRTTHAE GTRLSPFLIA PPSPISHTEP LAVKLQNGSP LAERPHPEVN GDTKWQSSQS  60
   61 CYGISHMKGS QSSHESPHED RGYSRCLQNG GIKRTVSEPS LSGLHPNKIL KLDQKAKGES 120
  121 NIFEESQERN HGKSSRQPNV SGLSDNGEPV TSTTQESSGA DAFPTRNYNG VEIQVLNEQE 180
  181 GEKGRSVTLL KNKIVLMPNG ATVSAHSEEN TRGELLEKTQ CYPDCVSIAV QSTASHVNTP 240
  241 SSQAAIELSH EIPQPSLTSA QINFSQTSSL QLPPEPAAMV TKACDADNAS KPAIVPGTCP 300
  301 FQKAEHQQKS ALDIGPSRAE NKTIQGSMEL FAEEYYPSSD RNLQASHGSS EQYSKQKETN 360
  361 GAYFRQSSKF PKDSISPTTV TPPSQSLLAP RLVLQPPLEG KGALNDVALE EHHDYPNRSN 420
  421 RTLLREGKID HQPKTSSSQS LNPSVHTPNP PLMLPEQHQN DCGSPSPEKS RKMSEYLMYY 480
  481 LPNHGHSGGL QEHSQYLMGH REQEIPKDAN GKQTQGSVQA APGWIELKAP NLHEALHQTK 540
  541 RKDISLHSVL HSQTGPVNQM SSKQSTGNVN MPGGFQRLPY LQKTAQPEQK AQMYQVQVNQ 600
  601 GPSPGMGDQH LQFQKALYQE CIPRTDPSSE AHPQAPSVPQ YHFQQRVNPS SDKHLSQQAT 660
  661 ETQRLSGFLQ HTPQTQASQT PASQNSNFPQ ICQQQQQQQL QRKNKEQMPQ TFSHLQGSND 720
  721 KQREGSCFGQ IKVEESFCVG NQYSKSSNFQ THNNTQGGLE QVQNINKNFP YSKILTPNSS 780
  781 NLQILPSNDT HPACEREQAL HPVGSKTSNL QNMQYFPNNV TPNQDVHRCF QEQAQKPQQA 840
  841 SSLQGLKDRS QGESPAPPAE AAQQRYLVHN EAKALPVPEQ GGSQTQTPPQ KDTQKHAALR 900
  901 WLLLQKQEQQ QTQQSQPGHN QMLRPIKTEP VSKPSSYRYP LSPPQENMSS RIKQEISSPS 960
  961 RDNGQPKSII ETMEQHLKQF QLKSLCDYKA LTLKSQKHVK VPTDIQAAES ENHARAAEPQ1020
 1021 ATKSTDCSVL DDVSESDTPG EQSQNGKCEG CNPDKDEAPY YTHLGAGPDV AAIRTLMEER1080
 1081 YGEKGKAIRI EKVIYTGKEG KSSQGCPIAK WVYRRSSEEE KLLCLVRVRP NHTCETAVMV1140
 1141 IAIMLWDGIP KLLASELYSE LTDILGKCGI CTNRRCSQNE TRNCCCQGEN PETCGASFSF1200
 1201 GCSWSMYYNG CKFARSKKPR KFRLHGAEPK EEERLGSHLQ NLATVIAPIY KKLAPDAYNN1260
 1261 QVEFEHQAPD CCLGLKEGRP FSGVTACLDF SAHSHRDQQN MPNGSTVVVT LNREDNREVG1320
 1321 AKPEDEQFHV LPMYIIAPED EFGSTEGQEK KIRMGSIEVL QSFRRRRVIR IGELPKSCKK1380
 1381 KAEPKKAKTK KAARKRSSLE NCSSRTEKGK SSSHTKLMEN ASHMKQMTAQ PQLSGPVIRQ1440
 1441 PPTLQRHLQQ GQRPQQPQPP QPQPQTTPQP QPQPQHIMPG NSQSVGSHCS GSTSVYTRQP1500
 1501 TPHSPYPSSA HTSDIYGDTN HVNFYPTSSH ASGSYLNPSN YMNPYLGLLN QNNQYAPFPY1560
 1561 NGSVPVDNGS PFLGSYSPQA QSRDLHRYPN QDHLTNQNLP PIHTLHQQTF GDSPSKYLSY1620
 1621 GNQNMQRDAF TTNSTLKPNV HHLATFSPYP TPKMDSHFMG AASRSPYSHP HTDYKTSEHH1680
 1681 LPSHTIYSYT AAASGSSSSH AFHNKENDNI ANGLSRVLPG FNHDRTASAQ ELLYSLTGSS1740
 1741 QEKQPEVSGQ DAAAVQEIEY WSDSEHNFQD PCIGGVAIAP THGSILIECA KCEVHATTKV1800
 1801 NDPDRNHPTR ISLVLYRHKN LFLPKHCLAL WEAKMAEKAR KEEECGKNGS DHVSQKNHGK1860
 1861 QEKREPTGPQ EPSYLRFIQS LAENTGSVTT DSTVTTSPYA FTQVTGPYNT FV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TET2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: