Protein Overview: Dcp2-PA

General Information:
Name(s) found:	Dcp2-PA / FBpp0075293 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|62484283\|ref\|NP_648805.2\| decapping protein 2, isoform A [Drosophila melanogaster] [NCBI NR] gi\|61678459\|gb\|AAF49579.4\| decapping protein 2, isoform A [Drosophila melanogaster] [NCBI NR] The gene Decapping protein 2 is referred to in FlyBase by the symbol Dmel\Dcp2 (CG6169, FBgn0036534). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15814087..15819519. It has the cytological map location 72A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; hydrolase activity; manganese ion binding. There is experimental evidence that it is involved in the biological process</span>: nuclear-transcribed mRNA catabolic process; gene silencing by miRNA. 7 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] (AE003529) CG6169 gene product [Drosophila melanogaster] [yeastflysequest.fasta] type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15817089,15818571..15818679); ID=FBpp0075293; name=Dcp2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,Fl [fly-100309-contam.fasta] CG6169-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15817089,15818571..15818679); ID=FBpp0075293; name=Dcp2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15817089,15818571..15818679); ID=FBpp0075293; name=Dcp2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Decapping protein 2, isoform A OS=Drosophila melanogaster GN=Dcp2 PE=2 SV=4 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:complement(15814545..15815111,15815171..15815908,15816063..15816281,15816347..15817089,15818571..15818679); ID=FBpp0075293; name=Dcp2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579,FlyMine:FBpp0075293,modMine:FBpp0075293; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(join(15825471..15825579,15823247..15823989,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075293; name=DCP2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579,FlyMine:FBpp0075293,modMine:FBpp0075293; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(15825471..15825579,15823247..15823989,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075293; name=DCP2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579,FlyMine:FBpp0075293,modMine:FBpp0075293; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q5U127, Decapping protein 2, isoform A OS=Drosophila melanogaster GN=DCP2 PE=1 SV=4 [DROME.fasta.20160308] FBpp0075293 type=protein; loc=3L:complement(join(15825471..15825579,15823247..15823989,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075293; name=DCP2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579,FlyMine:FBpp0075293,modMine:FBpp0075293; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(15825471..15825579,15823247..15823989,15822963..15823181,15822071..15822808,15821445..15822011)); ID=FBpp0075293; name=DCP2-PA; parent=FBgn0036534,FBtr0075538; dbxref=GB_protein:AAF49579.3,FlyBase_Annotation_IDs:CG6169-PA,FlyBase:FBpp0075293,GB_protein:AAF49579.4,REFSEQ:NP_648805,GB_protein:AAF49579,UniProt/TrEMBL:Q9VUU4,FlyMine:FBpp0075293,modMine:FBpp0075293; MD5=0949342c96ad3dccb2a982451dcdd176; length=791; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	791 amino acids
Gene Ontology:
Cellular Component:	cytoplasmic mRNA processing body [IDA]
Biological Process:	[NOT]nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP] gene silencing by miRNA [IMP] nuclear-transcribed mRNA catabolic process [IMP]
Molecular Function:	RNA binding [IEA] manganese ion binding [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIAPLINNA VAVVTASASA AVSASASVGS SSKDDNVNNL ALLASLTLQK VLNINNNNNQ  60
   61 HSKNNNHSDN SNSKQHEQQK QQQQPQRRNL DIKSEYDVLN QLLKTGAVFT ATPTAPIAIE 120
  121 RRKQTQQQQR PYAQQAHQQQ QQKQRLNSSI SSTHSSTSTN SSYGSSSSED AAGTSAPTGA 180
  181 GEVVTSAALT PRASTTKASS NKLPEKSKIP SDILDDLASR FIINVPDMEL NNLIRMCFQI 240
  241 ELAHWFYLDF FCAPESGEDG ETPKCVQRKL PSVGIKQFAM QLFQHIPFLN KHFGTVDQIL 300
  301 DEWKNYKLSV PTYGAILVSE DHNHCLLVQS YFARNSWGFP KGKINENEDP AHCATREVYE 360
  361 ETGFDITDLI DANDYIEAFI NYQYTRLYVV RNIPMDTQFA PRTRNEIKCC DWFRIDALPV 420
  421 NKNDAISKAK LGKTSNSFFM IMPFVKRLKK WVNDRKAGIE PRRRKFSGQQ SPKAASPTNM 480
  481 NGNCKKDVTG VRNESQRQRH KSMGDLDGVK LNNLNGKGTV GTGAGSAASA SATAAINSMN 540
  541 ICNSNGKRNK QNAAAGSNQA TPTTIATPMT SNGAVVGGTV SSKRQLFHSQ SQNDAQQSAS 600
  601 NEKIVSSFDL IRKEKQQQLK AAKAQKQQQQ QQQRSRTKSQ SDKQYNPQQP VKILGQQQPT 660
  661 TGMDLIAMLS AAAAAQKTPN NEQQTQEKQQ QQQRPRPASV SLNLGAGSAT GATTSAPDAQ 720
  721 YMHRLQRMAS GTNLRILKRA QSQQPQQHHQ QQLQLEQQQQ QQQQLGIDFT PNLNSWTNFS 780
  781 FTKNFIANVF C

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Dcp2-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: