Protein Overview: Trf2-PF, Trf2-PE...

General Information:
Name(s) found:	FBpp0303138 [FlyBase] Trf2-PF / FBpp0289804 [FlyBase] Trf2-PE / FBpp0111840 [FlyBase]
Description(s) found: Found 31 descriptions. SHOW ALL	type=protein; loc=X:join(8317598..8317608,8317761..8318068,8318130..8318348,8318409..8321920,8321980..8322238,8322310..8323148); ID=FBpp0303138; name=Trf2-PG; parent=FBgn0261793,FBtr0330105; dbxref=REFSEQ:NP_001259330,GB_protein:AGB95175,FlyBase:FBpp0303138,FlyBase_Annotation_IDs:CG18009-PG; MD5=2d1cc88f1843d3299fa8ba121e09f16b; length=1715; release=r5.56; species=Dmel; [FlyBase] The gene TATA box binding protein-related factor 2 is referred to in FlyBase by the symbol Dmel\Trf2 (CG18009, FBgn0026758). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8303305..8324228. It has the cytological map location 7E7-7E9. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 39 alleles are reported. The phenotype of these alleles is annotated with: salivary gland. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene TATA box binding protein-related factor 2 is referred to in FlyBase by the symbol Dmel\Trf2 (CG18009, FBgn0026758). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8303305..8324228. It has the cytological map location 7E7-7E9. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 39 alleles are reported. The phenotype of these alleles is annotated with: salivary gland. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1715 amino acids
Gene Ontology:
Cellular Component:	transcription factor complex [IDA] transcription factor TFIID complex [ISS]
Biological Process:	response to ecdysone [IMP] regulation of transcription, DNA-dependent [IEA] salivary gland cell autophagic cell death [IMP] pupal development [IMP] transcription initiation from RNA polymerase II promoter [ISS][TAS] regulation of transcription from RNA polymerase II promoter [IDA][IMP]
Molecular Function:	DNA binding [IEA] specific RNA polymerase II transcription factor activity [IDA][TAS] general RNA polymerase II transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSAVKKGDG SPTRILEEYQ VARDLRNEDL FPEHPVEHPD EDSDKENQSP NQSPNPRAIG  60
   61 DCEQGPDIGK DTLNPNEADQ FSSEEVEKNE ANSSCNESGG DARNSRDRLS SSHSEDEQLN 120
  121 QEYSTSSSGS TIGNREQGSD VGKDTSSRNE ADQFSNEEVE KNEANSSGNE SYGDACNSSD 180
  181 RLSSSNSEDE QLHQEYSTSS RGRTREYAQS DLNPGYQDLN IGNQDLNQVN REYQESNNEY 240
  241 QVSNQEYQHL NTEYQELNHG DQDSNDEYQE LNHGNQDSND EYQESNHGNQ DSNDEYQELN 300
  301 HSNQDSNDEY QELNHGDQDS SDEYQDLNHV NQDSNHEYQA WNHEYQDSNH EYQALNREYQ 360
  361 YPESDEEEAA RKRNIYTRLR SYACQVHLPR LGESEVDSDD RRHNPINQPF NQPINRPNQK 420
  421 SDSSLESSSP ERQDSESESR QASDEESSSG DSDYLIDPVT GWLSRRRETS TEREEKSDQS 480
  481 QQESSEEITD EQKEESDDVE QQSPAEHTSS DRRDHSPDKQ QNKRKSLGTG NSSYSKKPLL 540
  541 DGDKGDPRSH LSSLGSRRSL KRKWPFDCTD SKKFKPNLQS EEDKSEEEKR EDTESECSDE 600
  601 EDSDSSSFDT DSNSDSDSNL DLDSDSDSHS DFESSSSSEE SAQDPAPEGE TDQDPAPEGE 660
  661 ADQDPAPEGG VDQDPAPEGG VDQDPAPEGE VDQDPAPEGE SDQDLAPEGG VDQDPAPEFG 720
  721 TDQDPHPYYN DQDPAPYYDD QDPASYYDDH ICDSEEDYKP FIFSKERKFL KFVTNPLGDD 780
  781 KSSLDLSIQL YKVFGAYKLE DVYSSIDEEG QPEQDLQLKQ QQKHLKKYQK LQLVVFWHQE 840
  841 KFFSKEQLLL YEYLKLLLQK FFPQEQQEKR LQQEKLLQQE KLLQQEKRLQ QEKRLQQEKR 900
  901 LQQEKRLQQE KRLQQQKLLQ QQKLLQQEKL LQQQKLLQQE KLLQQEKLLQ QEKQLQQEKH 960
  961 LPQERQLQQD KVFLQLRQLQ QKKELEEQRE RKRHLFEQQK QFVLEKLRQQ KEQHRRQQNR1020
 1021 VKRERKLRQK KEKQRLEYER FLKEYREDCK RQLRLQREHY LIKIKQLEKA SQRSLKGNRK1080
 1081 HKLMQNDMVS IPVANLNGGL KAASSGSGVG VVTSGGVVSS AVLANAPRVY LTPSSTFMTN1140
 1141 RQMAGVASTG RMSGQVVGGS SGTASTAGTV RYFSQFSKMQ TAGGPSLQRK LANGDTIVLA1200
 1201 TGSKNMFLTS SENKANLPTV ASNGNGLITA KMDLLEEEVM QSITVIDDDD EEKKEVAEDE1260
 1261 EESSNNAKPI DLHQPIADNE HELDIVINNV VCSFSVGCHL KLREIALQGS NVEYRRENGM1320
 1321 VTMKLRHPYT TASIWSSGRI TCTGATSESM AKVAARRYAR CLGKLGFPTR FLNFRIVNVL1380
 1381 GTCSMPWAIK IVNFSERHRE NASYEPELHP GVTYKMRDPD PKATLKIFST GSVTVTAASV1440
 1441 NHVESAIQHI YPLVFDFRKQ RSAEELQHLR QKQRLQAGGD PHELEKNVLA DNKTASLDNI1500
 1501 FVNTTAAHSK SSSNDQTSAP ATILSSTVDS MPRLKQMVNY HQMMKQTQEE RRHIMFNGEK1560
 1561 ANPASTSSAA AAPSTSSSSS SSGDNICANA RRRATECWAT KLQNKRPRYN DPGTTGTINA1620
 1621 ASSTASAATS SLASQATHLR NPLKTAALAN ARMLGAKVTT CTRNSIIVQQ PQRIQMQQQQ1680
 1681 QQLQPQQQQT SFSPSEFDVD DLIEEEENNE LDMPF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: Trf2-PF, Trf2-PE...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: