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Protein Overview: mcm-6

General Information:
Name(s) found: mcm-6 / CE38018 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00003158 locus:mcm-6 DNA replication licensing factor mcm-6 status:Confirmed UniProt:P34647 protein_id:CAI46590.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 516 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    DNA replication initiation [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    DNA binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    DNA-dependent ATPase activity [IEALink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFLACHIQQ TESLVGGDAS GAVEETDYLD LWSKMSTEDR ATLKKMSDDK KIEKNIVDSL  60
   61 FPNIYGNHEV KLGVLLMLLG GVAKKSRDEG TSLRGDINVC LVGDPSTAKS QVLKAVEEFS 120
  121 PRAIYTSGKA SSAAGLTAAV VKDEESFEFV IEAGALMLAD NGVCCIDEFD KMDLKDQVAI 180
  181 HEAMEQQTIS ITKAGVKATL NARASILAAA NPVNGRYDRS RPLKYNVQMS APIMSRFDLF 240
  241 FVLVDECNEV TDYAIARRIL DNHRAISEHT ERDSVYKIDD IKKYIAFARC FKPKISDKAA 300
  301 ETLVREYKKL RMSDSNNAAT SSWRITVRQL ESLVRLSEAL ARLHCGKEVL VEHVEKAAEL 360
  361 LNKSIVRVEQ PDIALDDDDF DNNIMVVEAD KENQRGDDSM DHDGEKENAP KIDIAKLKIS 420
  421 FKEYKQLSDV LVLHMRSDED NQGEDEYDGV KQSALVEWYL STIEADLETE EDFNVQKTIC 480
  481 ERVIHRLIHQ DHVLLEVEQG EDPTLCVHPN YVIADE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] FFAS03 1.01 DNA replication initiator (cdc21/cdc54) N-terminal domain
    2 View Details [79..516] PSI-BLAST 8.154902 No description for 2dhrA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle