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Protein Overview: CE38201

General Information:
Name(s) found: CE38201 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00019168 status:Partially_confirmed UniProt:Q5CCJ2 protein_id:CCD72253.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 786 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    rRNA processing [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: rRNA (uridine) methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKVKIGKQ RRDKYYKLAK EAGYRSRAAF KLVQLNKRFE FLEKSRATVD LCAAPGGWMQ  60
   61 VASQFMPVSS LIVGVDLAPI KPIKNCIALQ GDITTNETRA AIKKELKTWS ADCVLHDGAP 120
  121 NVGLNWVHDA FQQNCLTLSA LKLATQILRK GGTFVTKVFR SNDYSCLIRV FEKLFKRVHV 180
  181 WKPAASRLES AEIFVVCEVY QKPDKVGAEY LDPKKVFANP DGSEGTKPNP QNLLIGKQKK 240
  241 AKAEGYDTDS LAIHSTINAT DFIKSSGYLD ILGTANVITL DDEKWKNHEK TTEEVIEYMN 300
  301 DVKVLGPREL RVLLRWRKSM LETLEEQRKA VEGEAKEVEI EENLTEEQLE DRAMAEIDEL 360
  361 IAKASEDEKA ALKKKKKKML KAKARVLKRR ELKMIIDGDE GPQAEDQEVF QLKKIRKAKE 420
  421 LAEITKDTQA PDFDMMEDGD SDEEEGLGEG EWETHGEEGE NSDEDENELI HTEKSGMSKM 480
  481 EKRNARTESW FEKEEISGLV SDEDDDDEMN AIEKHIGKNR SKKTENYENT VSFDDSKGKK 540
  541 KGKKGGKGGE DDGFNTNDAD EQASESESSD AEMDEVAKEK LSRFDAQIDL DDDDEEERYE 600
  601 DEGRRAAKRK CDKKIIGEDL KPVAKKRKLT PEQLAIGEQM IYSAKAARNL EDEAWNRYAN 660
  661 NDEDLPDWFA DDEKKHYFKQ TPVTKEQVAL YRERMREFNA RPSKKVAEAK ARKQKKMQRK 720
  721 LESAKKKAEG ILENDQMEHS EKVREMKKVY ANATRKEKKK VELVRMTKGK KGKTGRPNGQ 780
  781 YKLVDR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 77.0 RNA methyltransferase FtsJ
    2 View Details [219..425] deduced N/A No confident structure predictions are available.
    3 View Details [426..786] PSI-BLAST 13.69897 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.92746815303714 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.99461585647365 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.5931020126592 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.18991764495147 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.04296107639729 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.66871163498737 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.1103522853299 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  1.10713374933008 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.89325812193225 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • binding
    		•  0.777596419415505 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • RNA binding
    		•  0.417524996559564 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  0.364369105571521 bayes_pls_golite062009
  • O-methyltransferase activity
    		•  0.250946859465502 bayes_pls_golite062009
  • rRNA (guanine-N1-)-methyltransferase activity
    		•  0.234572322347698 bayes_pls_golite062009
  • tRNA (guanine) methyltransferase activity
    		•  0.203168546434167 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle