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Protein Overview: cka-2

General Information:
Name(s) found: cka-2 / CE38493 [WormBase]
Description(s) found:
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  • WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q2XN11 protein_id:CCD65408.1 [WormBase]
  • gi|71985811|ref|NP_001024481.1| Choline Kinase A family member (cka-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|62630063|gb|AAX88835.1| Choline kinase a protein 2, isoform b [Caenorhabditis elegans] [NCBI NR]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed [wormpep150.fasta]
  • 38493 WBGene00000510 locus:cka-2 status:Confirmed [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q2XN11_CAEEL protein_id:AAX88835.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q2XN11_CAEEL protein_id:AAX88835.1| [wormORF-contam.fasta]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed TR:Q2XN11 protein_id:AAX88835.1 [wormpep160-contam.fasta]
  • Choline kinase a protein 2, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Choline Kinase A family member (cka-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q2XN11 protein_id:AAX88835.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q2XN11 protein_id:CCD65408.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE38493 WBGene00000510 locus:cka-2 status:Confirmed UniProt:Q22942 protein_id:CCD65408.1 Choline kinase A2 [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
  • Isoform of Q22942, Isoform b of Choline kinase A2 OS=Caenorhabditis elegans GN=cka-2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 408 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: phosphopantetheine binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLVAEGHFR GMKELLSTMD LDTDANTIPE LKERAHMLCA RFLGGAWKTV PLEHLRISRI  60
   61 KGGMSNMLFL CRLSEVYPPI RNEPNKVLLR VYFNPETESH LVAESVIFTL LSERHLGPKL 120
  121 YGIFSGGRLE EYIPSRPLSC HEISLAHMST KIAKRVAKVH QLEVPIWKEP DYLCEALQRW 180
  181 LKQLTGTVDA EHRFDLPEEC GVSSVNCLDL ARELEFLRAH ISLSKSPVTF CHNDLQEGNI 240
  241 LLPKASSGNI RMPSLSDETQ ALGNSLSAFN PADPRLVLID FEYASYNYRA FDFANHFIEW 300
  301 TIDYDIDEAP FYKIQTENFP ENDQMLEFFL NYLREQGNTR ENELYKKSED LVQETLPFVP 360
  361 VSHFFWGVWG LLQVELSPVG FGFADYGRDR LSLYFKHKQL LKNLASHQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] PSI-BLAST 90.69897 Choline kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase activity
    		•  4.30960004746003 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  4.07995443484626 bayes_pls_golite062009
  • kinase activity
    		•  3.89987897070552 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.70039524176921 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.55773222358151 bayes_pls_golite062009
  • transferase activity
    		•  2.57136779276375 bayes_pls_golite062009
  • binding
    		•  1.64878945268884 bayes_pls_golite062009
  • ATP binding
    		•  1.52353103126485 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.48174269738296 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.45967951824395 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.24161418034479 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.23921774982777 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.22198325574141 bayes_pls_golite062009
  • nucleotide binding
    		•  1.21738858723976 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • protein binding
    		•  0.870256975882046 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.847174345238246 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  0.721451668935865 bayes_pls_golite062009
  • choline kinase activity
    		•  0.677058874011035 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.67181527739702 bayes_pls_golite062009
  • ethanolamine kinase activity
    		•  0.403804055728899 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.136035352478764 bayes_pls_golite062009
  • lipid kinase activity
    		•  0.0770938558959298 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.75

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle