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Protein Overview: CE39249

General Information:
Name(s) found: CE39249 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00018076 locus:pifk-1 status:Partially_confirmed UniProt:Q20077 protein_id:CCD70618.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 666 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phosphoinositide-mediated signaling [IEALink to PubMed article]
    phosphoinositide phosphorylation [IEALink to PubMed article]
    Molecular Function: phosphotransferase activity, alcohol group as acceptor [IEALink to PubMed article]
    1-phosphatidylinositol-3-kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSESDVEYT IKQPDLTDVP TQSAKNLADG TIIVGENDTS DKEIEIEKED TTKPTHDRQS  60
   61 WTMRLISSES FNAPMAVEYL NSIQDKPSLT FLGKRLFDLP EKDLDFYLPQ LMYLYVTKVD 120
  121 AASVSHAYIE ERNKKDAQFT VLCIWLLNCF TKNVPNKYEN HALMLKSLLS RSNVPGTSQS 180
  181 ADNMITLSLD RLEETNWTVG SSYGKSAGAL ARAAIQKEST LTAEHDSYEK SRCGPISTKL 240
  241 LTNQQNFIGR LVYIGVKLTE HHLLSSKQEK TIALQSELSM LNSMLPNSVW IPFDFENTMF 300
  301 NICVNESAVL NSKDKVPYVF FAEVIRSSPN YNSNIKTLSS VEPRIKKSQS ESVLLKNKSY 360
  361 HDSTDPSIAV FAESWAEKKA RIRGSSRYEN HQKWDLIPVI VKTGDDLSQE AFAQQLLFTF 420
  421 KDLWHEEGVP LYLRPYKIVC IGSDAGLIEP VLDTLSLHQI KRHLTNVFRM NGNVTTPSLK 480
  481 HHFENVFGPV NSETYVNAQK NFIQSTAAYS LVSYYLQLKD RHNGNILLDM DGHLIHIDYG 540
  541 FLLSSSPRNL GFETAPFKLT TEIIDVMGGI DSDMFLYFKS LLLRGLMAAR KHHRRIVSLA 600
  601 EIMSAGSKMQ CFRAGAETVR ALEARFHVSS TDEQLQQLVD TLVEGSRDSY TTRFYDSFQY 660
  661 YTNGIH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..666] PSI-BLAST 92.30103 Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.06347528042278 bayes_pls_golite062009
  • kinase activity
    		•  1.02409755159573 bayes_pls_golite062009
  • binding
    		•  0.965705916566869 bayes_pls_golite062009
  • protein kinase activity
    		•  0.933596056888996 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.904491209582148 bayes_pls_golite062009
  • transferase activity
    		•  0.467738620631271 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.453529572806301 bayes_pls_golite062009
  • catalytic activity
    		•  0.316052266554946 bayes_pls_golite062009
  • protein binding
    		•  0.113616704254907 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0300488593105301 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle