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Protein Overview: cfz-2

General Information:
Name(s) found: cfz-2 / CE39149 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000478 locus:cfz-2 status:Confirmed UniProt:G5ECQ2 protein_id:CCD62501.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 578 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: cell surface receptor linked signaling pathway [IEALink to PubMed article]
    Molecular Function: G-protein coupled receptor activity [IEALink to PubMed article]
    non-G-protein coupled 7TM receptor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRISVLFL LLGSCGALFG KRQKCEQITI PLCKGIGYNM TSFPNSYGHE KQEEAGLEVH  60
   61 QFYPLVEVGC FQHLKFFLCT MYTPICQENY DKPILPCMEL CVEARSKCSP IMAKYGFRWP 120
  121 ETLSCEALPK MSDQMSTGNI CAAPPDTPKK QHKGHHHKNQ NQNQNQNHNY SPDGPEVGIS 180
  181 KIDNEVIAGP SECQCTCNQP FQFVASEKSK VGNVTNCAYS CHSPALAESH SLVSNWMAFW 240
  241 SITCCVLASF TFLTFLIETD RFQYPERPIF MLAFCQLMVA VGFMIRYFVG HEEIACDSMR 300
  301 IKGADDNSGS LCFVVFLLTY FFGMAASVWW VILSLTWVLS AASKWSPEAI SSFSFHFHVV 360
  361 GWCLPAIQTV LVIVFNAIDG DPITGICYVG NTDLQFQRIF VLFPLLVYFI VGVLFLVIGF 420
  421 CNLWSIRNEV QKQHPSLESA HKITQLMSKI GIFSLLYTIP SLLIICVLFY EQNHRSLWEQ 480
  481 SQLCSCSPKQ TIGDSSLIIS LIKTCCMCIL GWTSGFWVCS TKTLSSWKNA ICCLGSSRSL 540
  541 PKYQPADILY AKSDMSSSQF YNTSLRHNHL YGGIPDKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] PSI-BLAST 37.221849 Frizzled 8 (FZ8)
    2 View Details [178..578] PSI-BLAST 45.522879 Rhodopsin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • Wnt receptor activity
    		•  5.34849208575619 bayes_pls_golite062009
  • Wnt-protein binding
    		•  4.48351937520811 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  4.38708793497137 bayes_pls_golite062009
  • receptor activity
    		•  4.1046853496316 bayes_pls_golite062009
  • signal transducer activity
    		•  3.17034085692897 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.17034085692897 bayes_pls_golite062009
  • binding
    		•  1.75284371400205 bayes_pls_golite062009
  • protein binding
    		•  1.1012033332744 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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