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Protein Overview: MYS2_DICDI

General Information:
Name(s) found: MYS2_DICDI [Swiss-Prot]
Description(s) found:
Found 4 descriptions.
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  • Myosin-2 heavy chain OS=Dictyostelium discoideum GN=mhcA PE=1 SV=3 [Swiss-Prot]
    • Organism: Dictyostelium discoideum
    Length: 2116 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IDA]
    actomyosin contractile ring [IDA]
    uropod [IDA]
    cell cortex [IDA]
    myosin II complex [IDA]
    myosin filament [IDA]
    actomyosin [IDA]
    Biological Process: pseudopodium retraction [IDA][IMP]
    bleb assembly [IMP]
    actin-myosin filament sliding [IDA]
    uropod retraction [IMP]
    protein localization [IMP]
    cytokinesis [IGI][IMP]
    cytoplasmic actin-based contraction involved in forward cell motility [IMP]
    filopodium assembly [IMP]
    cortical actin cytoskeleton organization [IDA][IMP]
    chemotaxis [IMP]
    negative regulation of actin filament polymerization [IMP]
    cellular component movement [IGI][IMP]
    culmination involved in sorocarp development [IMP]
    myosin filament assembly [IDA]
    contractile actin filament bundle assembly [IMP]
    Molecular Function: actin filament binding [IDA]
    actin-dependent ATPase activity [IDA]
    ATP binding [IDA]
    protein homodimerization activity [IDA]
    adenyl nucleotide binding [IDA]
    microfilament motor activity [IDA]
    motor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPIHDRTSD YHKYLKVKQG DSDLFKLTVS DKRYIWYNPD PKERDSYECG EIVSETSDSF  60
   61 TFKTVDGQDR QVKKDDANQR NPIKFDGVED MSELSYLNEP AVFHNLRVRY NQDLIYTYSG 120
  121 LFLVAVNPFK RIPIYTQEMV DIFKGRRRNE VAPHIFAISD VAYRSMLDDR QNQSLLITGE 180
  181 SGAGKTENTK KVIQYLASVA GRNQANGSGV LEQQILQANP ILEAFGNAKT TRNNNSSRFG 240
  241 KFIEIQFNSA GFISGASIQS YLLEKSRVVF QSETERNYHI FYQLLAGATA EEKKALHLAG 300
  301 PESFNYLNQS GCVDIKGVSD SEEFKITRQA MDIVGFSQEE QMSIFKIIAG ILHLGNIKFE 360
  361 KGAGEGAVLK DKTALNAAST VFGVNPSVLE KALMEPRILA GRDLVAQHLN VEKSSSSRDA 420
  421 LVKALYGRLF LWLVKKINNV LCQERKAYFI GVLDISGFEI FKVNSFEQLC INYTNEKLQQ 480
  481 FFNHHMFKLE QEEYLKEKIN WTFIDFGLDS QATIDLIDGR QPPGILALLD EQSVFPNATD 540
  541 NTLITKLHSH FSKKNAKYEE PRFSKTEFGV THYAGQVMYE IQDWLEKNKD PLQQDLELCF 600
  601 KDSSDNVVTK LFNDPNIASR AKKGANFITV AAQYKEQLAS LMATLETTNP HFVRCIIPNN 660
  661 KQLPAKLEDK VVLDQLRCNG VLEGIRITRK GFPNRIIYAD FVKRYYLLAP NVPRDAEDSQ 720
  721 KATDAVLKHL NIDPEQYRFG ITKIFFRAGQ LARIEEAREQ RISEIIKAIQ AATRGWIARK 780
  781 VYKQAREHTV AARIIQQNLR AYIDFKSWPW WKLFSKARPL LKRRNFEKEI KEKEREILEL 840
  841 KSNLTDSTTQ KDKLEKSLKD TESNVLDLQR QLKAEKETLK AMYDSKDALE AQKRELEIRV 900
  901 EDMESELDEK KLALENLQNQ KRSVEEKVRD LEEELQEEQK LRNTLEKLKK KYEEELEEMK 960
  961 RVNDGQSDTI SRLEKIKDEL QKEVEELTES FSEESKDKGV LEKTRVRLQS ELDDLTVRLD1020
 1021 SETKDKSELL RQKKKLEEEL KQVQEALAAE TAAKLAQEAA NKKLQGEYTE LNEKFNSEVT1080
 1081 ARSNVEKSKK TLESQLVAVN NELDEEKKNR DALEKKKKAL DAMLEEMKDQ LESTGGEKKS1140
 1141 LYDLKVKQES DMEALRNQIS ELQSTIAKLE KIKSTLEGEV ARLQGELEAE QLAKSNVEKQ1200
 1201 KKKVELDLED KSAQLAEETA AKQALDKLKK KLEQELSEVQ TQLSEANNKN VNSDSTNKHL1260
 1261 ETSFNNLKLE LEAEQKAKQA LEKKRLGLES ELKHVNEQLE EEKKQKESNE KRKVDLEKEV1320
 1321 SELKDQIEEE VASKKAVTEA KNKKESELDE IKRQYADVVS SRDKSVEQLK TLQAKNEELR1380
 1381 NTAEEAEGQL DRAERSKKKA EFDLEEAVKN LEEETAKKVK AEKAMKKAET DYRSTKSELD1440
 1441 DAKNVSSEQY VQIKRLNEEL SELRSVLEEA DERCNSAIKA KKTAESALES LKDEIDAANN1500
 1501 AKAKAERKSK ELEVRVAELE ESLEDKSGTV NVEFIRKKDA EIDDLRARLD RETESRIKSD1560
 1561 EDKKNTRKQF ADLEAKVEEA QREVVTIDRL KKKLESDIID LSTQLDTETK SRIKIEKSKK1620
 1621 KLEQTLAERR AAEEGSSKAA DEEIRKQVWQ EVDELRAQLD SERAALNASE KKIKSLVAEV1680
 1681 DEVKEQLEDE ILAKDKLVKA KRALEVELEE VRDQLEEEED SRSELEDSKR RLTTEVEDIK1740
 1741 KKYDAEVEQN TKLDEAKKKL TDDVDTLKKQ LEDEKKKLNE SERAKKRLES ENEDFLAKLD1800
 1801 AEVKNRSRAE KDRKKYEKDL KDTKYKLNDE AATKTQTEIG AAKLEDQIDE LRSKLEQEQA1860
 1861 KATQADKSKK TLEGEIDNLR AQIEDEGKIK MRLEKEKRAL EGELEELRET VEEAEDSKSE1920
 1921 AEQSKRLVEL ELEDARRNLQ KEIDAKEIAE DAKSNLQREI VEAKGRLEEE SIARTNSDRS1980
 1981 RKRLEAEIDA LTAQVDAEQK AKNQQIKENK KIETELKEYR KKFGESEKTK TKEFLVVEKL2040
 2041 ETDYKRAKKE AADEQQQRLT VENDLRKHLS EISLLKDAID KLQRDHDKTK RELETETASK2100
 2101 IEMQRKMADF FGGFKA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle