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Protein Overview: gi|2760368

General Information:
Name(s) found: gi|2760368 [NCBI NR]
Description(s) found:
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  • gi|2760368|gb|AAC38820.1| Shar pei/DRhoGEF2 [Drosophila melanogaster] [NCBI NR]
  • Shar pei/DRhoGEF2 [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • Shar pei/DRhoGEF2 OS=Drosophila melanogaster GN=RhoGEF2 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 2559 amino acids

    Gene Ontology:
    Cellular Component: lateral plasma membrane [IDA]
    apical part of cell [IDA]
    actomyosin contractile ring [IDA]
    basal part of cell [IDA]
    apical cortex [IDA]
    apical plasma membrane [IDA]
    actin cap [IDA]
    Biological Process: regulation of cell shape [IDA][IMP]
    ventral furrow formation [IMP]
    regulation of Rho protein signal transduction [IEA]
    spiracle morphogenesis, open tracheal system [IMP]
    posterior midgut invagination [IMP]
    germ-band extension [IMP]
    actin filament organization [IMP]
    anterior midgut invagination [IMP]
    pole cell development [IMP]
    cellularization [IMP]
    gastrulation [TAS]
    regulation of axonogenesis [IGI]
    morphogenesis of embryonic epithelium [IMP]
    regulation of embryonic cell shape [IGI][IMP][NAS]
    actin cytoskeleton reorganization [IMP]
    pseudocleavage during syncytial blastoderm formation [IMP]
    Molecular Function: protein binding [IEA]
    diacylglycerol binding [ISS]
    Rho guanyl-nucleotide exchange factor activity [IEA][ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDPSIKKRL LDLYTDEHEY DEVQEIPEES SIQPPETSTS HTSTNGSSHS GPGTATGPGA  60
   61 TSAGPSAGAP QSPVIVVDSV PELPAPKQKS VKNSKSKQKQ KQLANKSKIP RSPSLASSLS 120
  121 SLASSLSGHR DRDKDRDKDR ENQNAVPPQT PPLPPSYKQN QMNGDSTAAA GGGVSAPATP 180
  181 TTANNNNASH NNGSIMGGGV QLNQSDNSNP VLQAPGERSS LNLTPLSRDL SGGHTQESTT 240
  241 PATTPSTPSL ALPKNFQYLT LTVRKDSNGY GMKVSGDNPV FVESVKPGGA AEIAGLVAGD 300
  301 MILRVNGHEV RLEKHPTVVG LIKASTTVEL AVKRSQKLTR PSSVSVVTPS TPILSGRDRT 360
  361 ASITGPQPVD SIKRREMETY KIQTLQKMLE QEKLNLERLK SDQNNPSYKL SEANIRKLRE 420
  421 QLHQVGAEDA PTVKLQAAAG NKNTALLTPN QIQHLSASAT HSNQQFHHLH HHHNLHNNNY 480
  481 PPQQQPASTS PAFLSLLPRS LSSLSLGTRK NKTEKDLTTS SPFGLTTDFL QQQRMSHQAE 540
  541 SMSQSMHQHT STPTSQQFFH PHQQQHRFKE TGPTSKGKNK FLISRSLIEE DVPPPLPQRN 600
  601 PPRQLNLDLK NGNASPGGSH LVAPVSDLDR ATSPQLNRSQ QQQLPRSTDN SPSNAKSKRS 660
  661 KIKTKALSDP KMSTQMLLQM ESASAAGAAG GSIEVDGGPP PLPPRLPGMM TEDMSRGSCQ 720
  721 NLAQPNSVGT AFNYPLVSTT TAVQNDNLNI AFPLSQRPNI VQQLQQYQQQ QQHQMSGGQA 780
  781 TGALGQTPNL GKNKHRRVGS SPDNMHPRHP DRITKTTSGS WEIVEKDGES SPPGTPPLPY 840
  841 LSSSHMTVLE DPNENNRGAA AAGPGVFIES HQFTPMAGAS SPIPISLHSS HMHAAQSNDT 900
  901 QKEIISMEDE NSDLDEPFID ENGPFNNLTR LLEAENVTFL AIFLNYVISN SDPAPLLFYL 960
  961 ITELYKEGTS KDMRKWAYEI HSTFLVPRAP LSWYRQDESL AREVDNVLQL EYDKVEILRT1020
 1021 VFLRSRKRAK DLISEQLREF QQKRTAGLGT IYGPTDDKLA EAKTDKLREQ IIDKYLMPNL1080
 1081 HALIEDENGS PPEDVRKVAL CSALSTVIYR IFNTRPPPSS IVERVHHFVS RDKSFKSRIM1140
 1141 GKNRKMNVRG HPLVLRQYYE VTHCNHCQTI IWGVSPQGYH CTDCKLNIHR QCSKVVDESC1200
 1201 PGPLPQAKRL AHNDKISKFM GKIRPRTSDV IGNEKRSRQD EELDVELTPD RGQASIVRQP1260
 1261 SDRRPDANIS IRSNGNTSCN TSGLNTTDLQ SSFHGSCAND SINPGGGAGC NMDLSTSVAS1320
 1321 TTPSTSGSVA AGLSAFAELN ALDTVDKEAR RERYSQHPEH KSAPVSVNRS ESYKERLSNK1380
 1381 RNRNSRRKTS DPSLSSRPND EQLDLGLSNA TYVGSSNSSL SSAGGSESPS TSMEHFAAPG1440
 1441 AAGGVQVPPM GLNQNQHPHL LIQQHAQQYC QQDSFQAGLA GAAGSSAASN SSFWNAGHPL1500
 1501 PVARWTLESE DEDDVNEADW SSMVAAEVLA ALTDAEKKRQ EIINEIYQTE RNHVRTLKLL1560
 1561 DRLFFLPLYE SGLLSQDHLL LLFPPALLSL REIHGAFEQS LKQRRIEHNH VVNTIGDLLA1620
 1621 DMFDGQSGVV LCEFAAQFCA RQQIALEALK EKRNKDEMLQ KLLKKSESHK ACRRLELKDL1680
 1681 LPTVLQRLTK YPLLFENLYK VTVRLLPENT TEAEAIQRAV ESSKRILVEV NQAVKTAEDA1740
 1741 HKLQNIQRKL DRSSYDKEEF KKLDLTQHHL IHDGNLTIKK NPSVQLHGLL FENMIVLLTK1800
 1801 QDDKYYLKNL HTPLSITNKP VSPIMSIDAD TLIRQEAADK NSFFLIKMKT SQMLELRAPS1860
 1861 SSECKTWFKH FSDVAARQSK NRSKNASSNH DTSISDPALA AIPHSNTKES LELSTDTVQP1920
 1921 LAATATLTTT PLAPMLPIAT VTPAPATNNS NVSSLTGVQL RNPQRDATAS ESDADYVNTP1980
 1981 KPRSSQNEVN RTMSIRSTGE PIQKYSANGT EANDVTLRHS QSTRESVRPG STGEERNSTY2040
 2041 GMVGGNSKRD SASIVCSNNS NNTRTLLMQS PLVDPTAIQV SISPAHTAEP VLTPGEKLRR2100
 2101 LDASIRNDLL EKQKIICDIF RLPVEHYDQI VDIAMMPEAP KDSADIALAA YDQIQTLTKM2160
 2161 LNEYMHVTPE QEVSAVSTAV CGHCHEKEKL RKKVAPSSSF SSSPPPLPPP NRQHAQAQAQ2220
 2221 IPPSRLMPKL QTLDLDEVAI HEDDDGYCEI DELRLPAIPS KPHERPTTPL APFNTEPKTS2280
 2281 QSVIDASKRQ STDAVPEGLL EQEPLEGDKT ETKGEDNEVK TVPSDKLSES CNEERQCVEA2340
 2341 DITKEVADPT TSKNEAAASV DELPSQSREI KTAENASKSV ADKKEDNEET IEEGVASTVD2400
 2401 SSTQTSPTES PKETDKLTGG SSSTCGPNRI QHASVLEPSV PCHALSSIVT ILNEQISMLL2460
 2461 PKINERDMER ERLRKENQHL RELLSALHDR QRVDEVKETP FDLKKLMHAE DVEFDDDIDA2520
 2521 ISNSSLTPTP TPIPTASPSA SGQVETAEAM RITSTEDEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle