Protein Overview: SH2B1_MOUSE

General Information:
Name(s) found:	SH2B1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JC5886 signaling mediator - mouse [NCBI NR] gi\|172045833\|sp\|Q91ZM2.2\|SH2B1_MOUSE RecName: Full=SH2B adapter protein 1; AltName: Full=SH2 domain-containing protein 1B; AltName: Full=Pro-rich, PH and SH2 domain-containing signaling mediator; Short=PSM; AltName: Full=SH2-B PH domain-containing signali [NCBI NR] gi\|16226078\|gb\|AAL16069.1\|AF421138_1 Pro-rich, PH and SH2 domain-containing signaling mediator alpha [Mus musculus] [NCBI NR] SH2B adapter protein 1 OS=Mus musculus GN=Sh2b1 PE=1 SV=2 [Swiss-Prot] Pro-rich, PH and SH2 domain-containing signaling mediator alpha [ipi.MOUSE.v3.06.fasta] Pro-rich, PH and SH2 domain-containing signaling mediator alpha [Mus musculus]gi\|7513824\|pir\|\|JC5886 signaling mediator - mouse [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Pro-rich, PH and SH2 domain-containing signaling mediator alpha [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] SH2B adapter protein 1 (SH2 domain-containing protein 1B) (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2-B PH domain-containing signaling mediator 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Pro-rich, PH and SH2 domain-containing signaling mediator alpha [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 PRO-RICH, PH AND SH2 DOMAIN-CONTAINING SIGNALING MEDIATOR ALPHA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sh2b1 Isoform 1 of SH2B adapter protein 1 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Sh2b1 Pro-rich, PH and SH2 domain-containing signaling mediator alpha [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Sh2b1 Pro-rich, PH and SH2 domain-containing signaling mediator alpha ENSMUSG00000030733 IPI00875102 IPI00315068 IPI00283476 IPI00284016 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00284016.4\|SWISS-PROT:Q91ZM2-1 Tax_Id=10090 Gene_Symbol=Sh2b1 Isoform 1 of SH2B adapter protein 1 [ipi.MOUSE.fasta.20090209] Isoform 1 of SH2B adapter protein 1 OS=Mus musculus GN=Sh2b1 [011711_HMR.fasta] sp\|Q91ZM2\|SH2B1_MOUSE SH2B adapter protein 1 OS=Mus musculus GN=Sh2b1 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	756 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoplasm [IEA] membrane [IEA] ruffle [TAS]
Biological Process:	intracellular signaling pathway [IEA] cellular component movement [IDA] lamellipodium assembly [IDA]
Molecular Function:	protein binding [IPI] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGAPSPEDG VFPSPPALPP PPPPSWQEFC ESHARAAALD LARRFRLYLA SHPQYAEPGA  60
   61 EAAFSGRFAE LFLQHFEAEV ARASGSLSPP VLAPLSPGVE IPPSHDLSLE SCRVGGPLAV 120
  121 LGPSRSSEDL AGPLPSSVPS STTSSKPKLK KRFSLRSVGR SVRGSVRGIL QWRGAVDSPS 180
  181 QAGPLETTSG PPVLGGNSNS NSSGGAGTVG RALANDGTSP GERWTHRFER LRLSRGGGTL 240
  241 KDGAGMIQRE ELLSFMGAEE AAPDPAGVGR GGGAAGLTSG GGGQPQWQKC RLLLRSEGEG 300
  301 GGGSRLEFFV PPKASRPRLS IPCSTITDVR TATALEMPDR ENTFVVKVEG PSEYILETSD 360
  361 ALHVKAWVSD IQECLSPGPC PAISPRPMTL PLAPGTSFFT KDNTDSLELP CLNHSESLPS 420
  421 QDLLLGPSES NDRLSQGAYG GLSDRPSASF SPSSASIAAS HFDSMELLPP ELPPRIPIEE 480
  481 GPPAGTVHPL STPYPPLDTP EAATGSFLFQ GESEGGEGDQ PLSGYPWFHG MLSRLKAAQL 540
  541 VLEGGTGSHG VFLVRQSETR RGEYVLTFNF QGKAKHLRLS LNEEGQCRVQ HLWFQSIFDM 600
  601 LEHFRVHPIP LESGGSSDVV LVSYVPSQRQ QERSTSRDPA QPSEPPPWTD PPHPGAEEAS 660
  661 GAPEVAAATA AAAKERQEKE KAGSGGVQEE LVPVAELVPM VELEEAIAPG TEAQGGAGSS 720
  721 GDLEVSLMVQ LQQLPLGGNG EEGGHPRAIN NQYSFV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: SH2B1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: