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Protein Overview: EG10615

General Information:
Name(s) found: mtlA / EG10615 [EcoGene]
Description(s) found:
Found 11 descriptions.
SHOW ALL
  • mannitol-specific PTS enzyme: IIA, IIB and IIC components / Mannitol-specific Enzyme IIABC of PTS transport system [EcoGene]
    • Organism: Escherichia coli K-12
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDIKIKVQ SFGRFLSNMV MPNIGAFIAW GIITALFIPT GWLPNETLAK LVGPMITYLL  60
   61 PLLIGYTGGK LVGGERGGVV GAITTMGVIV GADMPMFLGS MIAGPLGGWC IKHFDRWVDG 120
  121 KIKSGFEMLV NNFSAGIIGM ILAILAFLGI GPIVEALSKM LAAGVNFMVV HDMLPLASIF 180
  181 VEPAKILFLN NAINHGIFSP LGIQQSHELG KSIFFLIEAN PGPGMGVLLA YMFFGRGSAK 240
  241 QSAGGAAIIH FLGGIHEIYF PYVLMNPRLI LAVILGGMTG VFTLTILGGG LVSPASPGSI 300
  301 LAVLAMTPKG AYFANIAGVC AAMAVSFVVS AILLKTSKVK EEDDIEAATR RMQDMKAESK 360
  361 GASPLSAGDV TNDLSHVRKI IVACDAGMGS SAMGAGVLRK KIQDAGLSQI SVTNSAINNL 420
  421 PPDVDLVITH RDLTERAMRQ VPQAQHISLT NFLDSGLYTS LTERLVAAQR HTANEEKVKD 480
  481 SLKDSFDDSS ANLFKLGAEN IFLGRKAATK EEAIRFAGEQ LVKGGYVEPE YVQAMLDREK 540
  541 LTPTYLGESI AVPHGTVEAK DRVLKTGVVF CQYPEGVRFG EEEDDIARLV IGIAARNNEH 600
  601 IQVITSLTNA LDDESVIERL AHTTSVDEVL ELLAGRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] MSA 2.619991 View MSA. No confident structure predictions are available.
    2 View Details [147..339] MSA 5.625993 View MSA. No confident structure predictions are available.
    3 View Details [340..504] PSI-BLAST 13.39794 STRUCTURE OF IIB DOMAIN OF THE MANNITOL-SPECIFIC PERMEASE ENZYME II
    4 View Details [505..637] PSI-BLAST 31.0 Phosphotransferase IIa-mannitol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
    		•  5.08041453921791 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  4.49138214292642 bayes_pls_golite062009
  • fructose transmembrane transporter activity
    		•  2.02791322402201 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  1.77053981674308 bayes_pls_golite062009
  • transporter activity
    		•  1.6837050020547 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.5685227361887 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.38987536600292 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.32293422112884 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.217268678967 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.12964417923438 bayes_pls_golite062009
  • hexose transmembrane transporter activity
    		•  0.80355002679172 bayes_pls_golite062009
  • binding
    		•  0.472595683811139 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.37663629577414 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0296784994545702 bayes_pls_golite062009
    4
    Term Confidence Notes
  • protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
    		•  4.89047341597444 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  3.92377913213665 bayes_pls_golite062009
  • transporter activity
    		•  2.16741930408232 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.05879816720019 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.87457143976439 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.82451780056478 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.7251575499811 bayes_pls_golite062009
  • binding
    		•  0.396676636991646 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.19707628828681 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.12881601139602 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.10209580008722 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle