Protein Overview: ATP4A_RAT

General Information:
Name(s) found:	ATP4A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A25344 H+/K+-exchanging ATPase (EC 3.6.3.10) alpha chain, gastric specific - rat [NCBI NR] gi\|203037\|gb\|AAA66036.1\| H+,K+-ATPase [Rattus norvegicus] [NCBI NR] gi\|114343\|sp\|P09626.3\|ATP4A_RAT RecName: Full=Potassium-transporting ATPase alpha chain 1; AltName: Full=Proton pump; AltName: Full=Gastric H(+)/K(+) ATPase subunit alpha [NCBI NR] Potassium-transporting ATPase alpha chain 1 OS=Rattus norvegicus GN=Atp4a PE=1 SV=3 [Swiss-Prot] Potassium-transporting ATPase alpha chain 1 (Proton pump) (Gastric H+/K+ ATPase alpha subunit)gi\|92352\|pir\|\|A25344 H+/K+-exchanging ATPase (EC 3.6.3.10) alpha chain, gastric specific - ratgi\|203037\|gb\|AAA66036.1\| H+,K+-ATPase [nrdb_11152004_Chlamydomonas] Potassium-transporting ATPase alpha chain 1 (Proton pump) (Gastric H(+)/K(+) ATPase subunit alpha) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] H+,K+-ATPase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Potassium-transporting ATPase alpha chain 1 (Proton pump) (Gastric H+/K+ ATPase subunit alpha) [nr-271106-contam.fasta] Potassium-transporting ATPase alpha chain 1 OS=Rattus norvegicus GN=Atp4a [011711_HMR.fasta] Potassium-transporting ATPase alpha chain 1 OS=Rattus norvegicus GN=Atp4a PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1033 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] plasma membrane [UNKNOWN][IEA] apical plasma membrane [IDA]
Biological Process:	gastric acid secretion [TAS] potassium ion transport [IEA] ATP hydrolysis coupled proton transport [IEA] response to drug [UNKNOWN][IEA] metabolic process [IEA] pH reduction [UNKNOWN][IEA] ATP biosynthetic process [IEA] regulation of proton transport [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] magnesium ion binding [IEA] ATP binding [IEA] monovalent inorganic cation transmembrane transporter activity [IEA] protein heterodimerization activity [UNKNOWN][IEA] hydrogen:potassium-exchanging ATPase activity [UNKNOWN][TAS] hydrolase activity [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKENYELYS VELGTGPGGD MAAKMSKKKA GGGGGKKKEK LENMKKEMEM NDHQLSVSEL  60
   61 EQKYQTSATK GLKASLAAEL LLRDGPNALR PPRGTPEYVK FARQLAGGLQ CLMWVAAAIC 120
  121 LIAFAIQASE GDLTTDDNLY LALALIAVVV VTGCFGYYQE FKSTNIIASF KNLVPQQATV 180
  181 IRDGDKFQIN ADQLVVGDLV EMKGGDRVPA DIRILSAQGC KVDNSSLTGE SEPQTRSPEC 240
  241 THESPLETRN IAFFSTMCLE GTAQGLVVST GDRTIIGRIA SLASGVENEK TPIAIEIEHF 300
  301 VDIIAGLAIL FGATFFVVAM CIGYTFLRAM VFFMAIVVAY VPEGLLATVT VCLSLTAKRL 360
  361 ASKNCVVKNL EAVETLGSTS VICSDKTGTL TQNRMTVSHL WFDNHIHTAD TTEDQSGQTF 420
  421 DQSSETWRAL CRVLTLCNRA AFKSGQDAVP VPKRIVIGDA SETALLKFSE LTLGNAMGYR 480
  481 DRFPKVCEIP FNSTNKFQLS IHTLEDPRDP RHLLVMKGAP ERVLERCSSI LIKGQELPLD 540
  541 EQWREAFQTA YLSLGGLGER VLGFCQLYLN EKDYPPGYTF DVEAMNFPSS GLCFAGLVSM 600
  601 IDPPRATVPD AVLKCRTAGI RVIMVTGDHP ITAKAIAASV GIISEGSETV EDIAARLRMP 660
  661 VDQVNKKDAR ACVINGMQLK DMDPSELVEA LRTHPEMVFA RTSPQQKLVI VESCQRLGAI 720
  721 VAVTGDGVND SPALKKADIG VAMGIAGSDA AKNAADMILL DDNFASIVTG VEQGRLIFDN 780
  781 LKKSIAYTLT KNIPELTPYL IYITVSVPLP LGCITILFIE LCTDIFPSVS LAYEKAESDI 840
  841 MHLRPRNPRR DRLVNEPLAA YSYFQIGAIQ SFAGFADYFT AMAQEGWFPL LCVGLRPQWE 900
  901 DHHLQDLQDS YGQEWTFGQR LYQQYTCYTV FFISIEMCQI ADVLIRKTRR LSAFQQGFFR 960
  961 NRILVIAIVF QVCIGCFLCY CPGMPNIFNF MPIRFQWWLV PMPFGLLIFV YDEIRKLGVR1020
 1021 CCPGSWWDQE LYY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ATP4A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: