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Protein Overview: PNP

General Information:
Name(s) found: PNP [HGNC (HUGO)]
Description(s) found:
Found 26 descriptions.
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  • purine nucleoside phosphorylase [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 289 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENGYTYEDY KNTAEWLLSH TKHRPQVAII CGSGLGGLTD KLTQAQIFDY GEIPNFPRST  60
   61 VPGHAGRLVF GFLNGRACVM MQGRFHMYEG YPLWKVTFPV RVFHLLGVDT LVVTNAAGGL 120
  121 NPKFEVGDIM LIRDHINLPG FSGQNPLRGP NDERFGDRFP AMSDAYDRTM RQRALSTWKQ 180
  181 MGEQRELQEG TYVMVAGPSF ETVAECRVLQ KLGADAVGMS TVPEVIVARH CGLRVFGFSL 240
  241 ITNKVIMDYE SLEKANHEEV LAAGKQAAQK LEQFVSILMA SIPLPDKAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..289] PSI-BLAST 105.0 CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH IMMUCILLIN H

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • S-methyl-5-thioadenosine phosphorylase activity
    		•  3.89303327575747 bayes_pls_golite062009
  • purine-nucleoside phosphorylase activity
    		•  3.68206997938506 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  3.66765825367784 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  2.28129906270728 bayes_pls_golite062009
  • catalytic activity
    		•  2.18268586151113 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.01261001022129 bayes_pls_golite062009
  • binding
    		•  1.58090357201399 bayes_pls_golite062009
  • nicotinamide riboside hydrolase activity
    		•  1.38986205931368 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  1.38135070025071 bayes_pls_golite062009
  • protein binding
    		•  1.28444435808613 bayes_pls_golite062009
  • nucleoside binding
    		•  1.11256863177576 bayes_pls_golite062009
  • purine binding
    		•  1.00226077276304 bayes_pls_golite062009
  • nucleobase binding
    		•  0.914372836742171 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle