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Protein Overview: gi|24935322, gi|...

General Information:
Name(s) found: gi|24935322 [NCBI NR]
gi|23683342 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|24935322|gb|AAN64156.1| DNA ligase 1 precursor [Plasmodium falciparum] [NCBI NR]
  • gi|23683342|gb|AAL59668.2| DNA ligase 1 [Plasmodium falciparum] [NCBI NR]
    • Organism: Plasmodium falciparum
    Length: 912 amino acids

    Gene Ontology:
    Cellular Component: replication fork [ISSLink to PubMed article]
    apicoplast [ISSLink to PubMed article]
    Biological Process: lagging strand elongation [ISSLink to PubMed article]
    DNA ligation [ISSLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFLILVVLI KMVVCKIINY VRSDYNFMLS FLRTRKIFSH KKIYFNFKVS KNITKNSSSN  60
   61 SYSDILKCFS FPRKGTNDKT KENETFEKGE VKEEEEEKDK NVKRKIINES SKNKRAKVKN 120
  121 ENDVIKKGSL FNCVVREDEK VNDLSSPKFN PVHFNINDLY LSEKDKEKHK FKDSLLFTFL 180
  181 TNAFNQIEEL KGSGTGSKKN VSIILSNIFR VLIYYSPNDL IPAVYITLNK VAPDYLNVEA 240
  241 GVGEALILKT MSEAYSRTES SIKKDLQQIE DLGIIAENCS CKMRTIFPLP RLTIQSVFHE 300
  301 LKSIPNLIGS NSQQKKREVI KKLLVSAKTS EAKYIVRFLQ QRLRIGVNSA TVVQALSYAF 360
  361 ILTRPSIPDD IIKRGKEINE NLINGKLDGT NNLINKSNNK TEEWLTQSGD RNCIKEENLN 420
  421 DELLSKDDIN KCENMDSLIN EIRIRNEKIN KPNIFYNLIE KVGDTRLLPL FFKELKNIYC 480
  481 EENNDIDIFE CMEKSVKSAL CELPNIEIII QNLLNGDDMN TLSKKCTVKT GIPVQPMLAK 540
  541 PTKGVQEVLD RFNNVTFTCE YKYDGERAQI HYIDKDNIKI FSRNLETMTE KYPDVIQIIK 600
  601 DQIGENVKEC IIDSEVVAYD IVNNKILPFQ VLTTRKRKDV DIENIKVKVC LFPFDLICCN 660
  661 GIPVIKEPLA VRRKLLYSLL KSKDGVLSYA THSEMNNIED IDMFLQDAIE NNCEGLMVKT 720
  721 LVENASYEPS RRSLNWLKVK KDYVEGLSDS VDLVPIAGYY GKGKRSGVYG AFVLAAYNSE 780
  781 TENFQTVCKA GTGFSDEILS TLYETLSEKI IPNKKSYYEV SDKLNPDVWF DAHYVWEVKA 840
  841 ADLSLSPVHT AAIGIYADDK GIGLRFPRFL RLREDKNAEQ ATTTQQIVDF YEAQFSSNKN 900
  901 KNIDYNDDTE SE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] MSA 18.179996 View MSA. No confident structure predictions are available.
    2 View Details [218..912] PSI-BLAST 165.0 Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.62364941193231 bayes_pls_golite062009
  • ligase activity
    		•  0.85267344624274 bayes_pls_golite062009
  • ligase activity, forming phosphoric ester bonds
    		•  0.81722565837488 bayes_pls_golite062009
  • DNA ligase activity
    		•  0.712397444123471 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle