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Protein Overview: unc-26

General Information:
Name(s) found: unc-26 / CE40972 [WormBase]
Description(s) found:
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  • WBGene00006763 locus:unc-26 status:Confirmed UniProt:G5EDR8 protein_id:CAN86614.1 [WormBase]
  • ref|NP_502551.2| UNCoordinated locomotion UNC-26, synaptojanin (56.5 kD) (unc-26) [Caenorhabditis elegans] [NCBI NR]
  • gi|193206406|ref|NP_001122785.1| UNCoordinated family member (unc-26) [Caenorhabditis elegans] [NCBI NR]
  • gi|148473243|emb|CAN86614.1| C. elegans protein JC8.10c, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|10567761|gb|AAG18576.1|AF283324_1 synaptojanin UNC-26C [Caenorhabditis elegans] [NCBI NR]
  • UNCoordinated locomotion UNC-26, synaptojanin (56.5 kD) (unc-26) [Caenorhabditis elegans]gi|10567761|gb|AAG18576.1| synaptojanin UNC-26C [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE40972 WBGene00006763 locus:unc-26 status:Confirmed UniProt:Q9GT40_CAEEL protein_id:CAN86614.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE40972 WBGene00006763 locus:unc-26 status:Confirmed UniProt:Q9GT40_CAEEL protein_id:CAN86614.1| [wormORF-contam.fasta]
  • synaptojanin UNC-26C [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE40972 WBGene00006763 locus:unc-26 status:Confirmed TR:Q9GT40 protein_id:CAN86614.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE40972 WBGene00006763 locus:unc-26 status:Confirmed UniProt:Q9GT40 protein_id:CAN86614.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE40972 WBGene00006763 locus:unc-26 status:Confirmed UniProt:G5EDR8 protein_id:CAN86614.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of G5ECL2, Synaptojanin UNC-26C OS=Caenorhabditis elegans GN=unc-26 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [ISSLink to PubMed article]
    Biological Process: cytoskeleton organization [IMPLink to PubMed article]
    acetylcholine transport [IMPLink to PubMed article]
    endosome organization [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    regulation of forward locomotion [IMPLink to PubMed article]
    regulation of backward locomotion [IMPLink to PubMed article]
    positive regulation of muscle contraction [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    synaptic vesicle uncoating [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    synaptic vesicle transport [IMPLink to PubMed article]
    vesicle organization [IMPLink to PubMed article]
    synaptic vesicle endocytosis [IMPLink to PubMed article]
    muscle contraction [IMPLink to PubMed article]
    Golgi vesicle uncoating [IMPLink to PubMed article]
    synaptic vesicle budding from presynaptic membrane [IMPLink to PubMed article]
    positive regulation of neurotransmitter secretion [IMPLink to PubMed article]
    gamma-aminobutyric acid transport [IMPLink to PubMed article]
    Molecular Function: inositol or phosphatidylinositol phosphatase activity [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRGIRIWR RNDARFQPSI LVEKNGLDGS LLFQGGAIAT LDSDSTDVER RSYQKIVDAY  60
   61 GILGVLAITK DEAVLVAVTG VLSVGQLYGA DILKITNVEF ISLRTFGSVE NVDSRIIDLQ 120
  121 RLLSSQMFYF SSLQSYDLTR SAQHRDSHDC SDARFFWNRS LHFSFQRYGI DTDNWLLKCM 180
  181 AGSVLVRVVY VGANTGRVAL ISRLSCERVG TRFNVRGANY LGNVANFVET EQLLLFDEKE 240
  241 CSLLQIRGSI PLFWEQPGVN VGSHKVKLRA FETSLPAYHR HLSQLQHRYG EFAIVNLLGR 300
  301 KEGERVLGDA FKTQHKSSHF APLVDFIDFD YHAQMKISKE AIVQLKKKMS PHMTKHGFFY 360
  361 SMGKEIVKRQ TGVIRTNCLD CLDRTNAVQT AIGLQMSHDQ VAFLNLNAGK VNVEQRVEEI 420
  421 LRDLWQKNGD QCSTIYAGTG ALDGKSKLKD ASRSLARTIQ NNLMDGAKQE SFDLFLTGAA 480
  481 YDPRLFDRAC NILPPSLIQG LF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..150] MSA 5.146993 View MSA. No confident structure predictions are available.
    2 View Details [151..364] MSA 3.154979 View MSA. No confident structure predictions are available.
    3 View Details [365..436] deduced N/A No confident structure predictions are available.
    4 View Details [437..502] MSA 7.139996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle