Protein Overview: itr-1

General Information:
Name(s) found:	itr-1 / CE37905 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00002173 locus:itr-1 Inositol 1,4,5-trisphosphate receptor itr-1 status:Confirmed UniProt:Q9Y0A1 protein_id:CCD63763.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	2892 amino acids
Gene Ontology:
Cellular Component:	membrane [IDA][IEA] endoplasmic reticulum [TAS] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of pharyngeal pumping [IGI][IMP] ion transport [IEA] muscle contraction [IMP] calcium ion transport [IEA] cell adhesion [IEA] blood coagulation [IEA] defecation [IMP] reproduction [IMP ] rhythmic behavior [IMP] elevation of cytosolic calcium ion concentration [IDA]
Molecular Function:	inositol-1,4,5-trisphosphate receptor activity [ISS] ion channel activity [IEA] calcium channel activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSYGRVRK KVSIISIPEF VPEHYEYENE TTASGGASGG GSTRIEFDFD DFEEQIMRKS  60
   61 SMALPSRKLT IANSIDHGNN GNLHIGDIIS LYTESSSNQE QRGFLSTLGL VDDRCIVELK 120
  121 DGRPESPPKK FRDCLFKVCP VNRYAAQKHL WTEQKRFQTG DSMFDDDLMN KLKVAADKER 180
  181 EENESEFQKT LGNVIQYGSM VQLLHVKSNK YITVQKNSPA KRERNAMKVY LDRAGNEGSW 240
  241 FIIEPAYKHY AIGDNVSAGN KISLIPNSVS TTQAGHVKSQ LHLSSFNLLD HQSAAEVNCL 300
  301 NEPTEWQVFM FLLFDENQQN SVKSGDVVRL FHADQQTFLT LDTIPKQNPP TDVVFLRMTN 360
  361 RPSAADATSS RALWEVQVVQ TNAYRGGTAK WNKAYRFKHL ATDMYLSAEP SQVQVKPAMN 420
  421 GRRASLIYSK TNNPMAMYSD GPNGVTNEST DTTQQNIPSV WVLGPTKSEF PEEDANLLFQ 480
  481 LDPSTFMKSN KEVPRRSYVR LLHQSSDKWV HATNATEKQN LHYSSKNEKG WVKVICEKNR 540
  541 VDKETFALLP VNPDEVRDLD FANDACKALR NFIKLIKIGQ VISKESINST TQLLIDCILF 600
  601 VTNSSDHLAD PLKISDFSPS RDRQKLLREQ EVLNQVFLLL KAPFLPRQGT TELGPLLSSP 660
  661 SELSDSRNEI FKTMFQLCYC LLKYSQVSYR KNQEFLAEKF GEIQEQIGFD LMAEDTMTAV 720
  721 LHNNPKLLEK YVKTPHVERF VELVRNNRQG KFLDYLADLC VCRGEANKKI QELICTSVLS 780
  781 SKHRDIFMDT KIIDGEIEVG WAPNFRKLVD IAEGAKSNSD DAEHLDYYRH QLDLLSQMCQ 840
  841 EQQYLAIDPP PERRLMNISQ QLPAELVLQC MSDNRLPYDL RGSFTRLMLH LHVVRGSPMS 900
  901 AIRHARLWWS IPENVNVSTY ESVSVEAYSD GSRMRIGEGI AHKVLATVET YLMGLRNQSM 960
  961 EERQSVNSSK LTYEIVNLAK ALAQFNFYSF NDLLQLTQNL LAIINEGPAT EQVPSHRAMV1020
 1021 NAIRNMSKSM MRGGNKENSK DLAKTPSVTA EEAGRTKEGR ALNVKTKLIV AEILQFVMDV1080
 1081 RRDYRITMAL SWFKNVFPCD EDGSLMHSAS INERMASELY DAIYRSSGHE LHLDGRDGQL1140
 1141 LLAILLQMTM SDYPPLTSIA LKVFFRHFTQ YQELLEDLKQ VQLLVSNNDV ENYRQIDRDL1200
 1201 FILKNLTEKS ELWVHGDRHH SIDTKEVDEK ERTTEHDLLD HDLKSPRAFD SGDSMEALMA1260
 1261 VLNEHYPSIR NECLQLLNRL LIKDDRNDAA VALQELSDKA PLIAYPLIRQ MLVRLTGMCY1320
 1321 RKGDPKPDTM NQQLLKNMRV YEVVLEFISV PHDKKHDHDM MKLITLSHEF LRSFCKTNKE1380
 1381 NQSRLYKFIS YEKDAKEGML RVETIEEVGT LVAIFRNNRE LASNVPEELI AHIVGLIEHN1440
 1441 SRNPIFLELL QALVCVYDKE IESGQEKVAN EICAASDEVR QLYVDNASFE ELEAMMKDEK1500
 1501 ESKGRSSDSR RKLKYHIELV RLLAMCTRGK NGNTELKCAS QIPMDHIVRV VTAKQCLVEV1560
 1561 KTVYLQLLLH CYIDTDAEMK DAYKTEYVDH ILNNLLEDIR SLRVEKLTGA ETATLEHYIC1620
 1621 HTVTEVLIKF FEAPYSALQQ AKVDVHHHKK TFSEVLLELT YLEKGKLRGS KSSRNWYRVA1680
 1681 ECIKRLTKWA EEHNITLPAT LAGPQMSGQT SVRQKWQQAA SSAKWIGIGK RLNRQNTLNP1740
 1741 GHRLYGTSNS MTEHTSANVV TCYHMMIGEF KFYLHPLHAA EGSVLVEVLH TPELLFPEGS1800
 1801 ALRDQCARGG VVAKLIQHCK TLMQNKQDNL CARVLQTLCK MCDCTKQQLT HQGQQLRQLL1860
 1861 LQRYFGHHNN HHPPLDRQQS KIGEVIEAVK EKKEETWSQE RDLYAIQCKL NDAGASDLVT1920
 1921 DIIIMEPSRE IFLKAIHLAR ALLHEGNDKV QHSFYMRMKQ KDIHEPFFKA ILTRIQTAQN1980
 1981 RLKSDMMSCS DSKPKVSLSA TVSRRSSTVL TPLIDAGDTG FNGALFEVPQ QVRHPSISEM2040
 2041 SQLSNDLTHS IPDLAPYQDE EKSTDALPPE VALVEPILRV LQLLCENHNS LLQNFLRKQS2100
 2101 DRTNHNLVSE TLSFLDTVCG STKGSLGVFG EIGEHNFSLI TQTLATLTEF CQGPCHENQN2160
 2161 TMAMQENGLN IIISLVLNEI KPLADDHMEL ALEIKSQASK LLLAIMESRH DGENANRVLR2220
 2221 NMANMSGGPK QLVHAIKQAY EMTNSNHHML KSISRDLFRQ AEDDLKKKSG PQITVNTVTL2280
 2281 PEINVDASGI VSIHTEKNIS SSLDDKFNDD DIPSVDPREV GHNIYILAHQ LAIHDGELEI2340
 2341 WLDGSDEKKD DLTREALNYY KERTAQIEIV RRDRTLERVV FPINDICSYL TKDTKDYVYN2400
 2401 NTERDNQGSK VTEFFDEWET MYHEMIWQRK LQDRKWLSWC AFRLPLWTRL SFHFAFIVNA2460
 2461 LVARYYPLPE HSNSSISLGN LYSWFAVFSS FLLAHYLRHD KIYLHKTSLL ILASLCFLLL2520
 2521 SSIGVTLTLY IFGILQLVNK IVHVVAFVSN KGLEDRPIAE ILACRNLHYL LVYLFICILG2580
 2581 LLVHPMIYCI LLFDIIFTEE TLQNVIASVT RNYQSIVWTG LLALILLYFF SILGFLYFRH2640
 2641 DFYLEVDPVE NDSSATISSG IPSETCPSEG CPGLQPSEKD DNDDEKKVKS CETLWMCILQ2700
 2701 TGYQGLRNGG GIGDVLRNPA PWEDMFIWRV AYDMTFFVVL IVIVLNLIFG VIIDTFGDLR2760
 2761 AEKNEKEQIL KNNCFICGLD RSRFDNRSVT FETHRETEHN IWHYLYYIVM LQIKDETEFT2820
 2821 GPESYVAQCV KDRNLDWFPR MQALSLQDSE LDTDQSEVKQ MKDQLLQMMT LMREIISQNE2880
 2881 ESRAFMEQFQ PR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: itr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: