Protein Overview: ACTN4_RAT

General Information:
Name(s) found:	ACTN4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|77539778\|ref\|NP_113863.2\| alpha actinin 4 [Rattus norvegicus] [NCBI NR] gi\|62639279\|ref\|XP_579522.1\| PREDICTED: alpha actinin 4 [Rattus norvegicus] [NCBI NR] gi\|38197444\|gb\|AAH61788.1\| Actinin alpha 4 [Rattus norvegicus] [NCBI NR] gi\|182705246\|sp\|Q9QXQ0.2\|ACTN4_RAT RecName: Full=Alpha-actinin-4; AltName: Full=Non-muscle alpha-actinin 4; AltName: Full=F-actin cross-linking protein [NCBI NR] gi\|149056431\|gb\|EDM07862.1\| rCG54533, isoform CRA_a [Rattus norvegicus] [NCBI NR] Alpha-actinin-4 OS=Rattus norvegicus GN=Actn4 PE=1 SV=2 [Swiss-Prot] Actn4 protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 alpha actinin 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Alpha actinin 4 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] Tax_Id=10116 Actn4 protein [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] alpha actinin 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG54533, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Actinin alpha 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ACTN4 PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Actn4 Alpha-actinin-4 [rat-ipi-250309-contam.fasta] Alpha-actinin-4 OS=Rattus norvegicus GN=Actn4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	911 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] perinuclear region of cytoplasm [UNKNOWN][IEA] ribonucleoprotein complex [UNKNOWN][ISS] cytoplasm [UNKNOWN][IDA] stress fiber [IDA] actin cytoskeleton [UNKNOWN] pseudopodium [IEA] protein complex [UNKNOWN][IDA] nucleolus [UNKNOWN][IEA] cortical cytoskeleton [UNKNOWN][IEA]
Biological Process:	response to hypoxia [IEP] protein transport [IEA] negative regulation of cellular component movement [IEA] positive regulation of cellular component movement [UNKNOWN][IEA] regulation of apoptosis [IMP] actin filament bundle assembly [IEA] positive regulation of pinocytosis [IEA]
Molecular Function:	actin filament binding [UNKNOWN][IEA] protein binding [UNKNOWN][IPI] calcium ion binding [IEA] protein N-terminus binding [IPI] protein complex binding [IPI] nucleoside binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDYHAANQA YQYGPSSGGN GTGGGGGMGD YMAQEDDWDR DLLLDPAWEK QQRKTFTAWC  60
   61 NSHLRKAGTQ IENIDEDFRD GLKLMLLLEV ISGERLPKPE RGKMRVHKIN NVNKALDFIA 120
  121 SKGVKLVSIG AEEIVDGNAK MTLGMIWTII LRFAIQDISV EETSAKEGLL LWCQRKTAPY 180
  181 KNVNVQNFHI SWKDGLAFNA LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM 240
  241 LDAEDIVNTA RPDEKAIMTY VSSFYHAFSG AQKAETAANR ICKVLAVNQE NEHLMEDYER 300
  301 LASDLLEWIR RTIPWLEDRV PQKTIQEMQQ KLEDFRDYRR VHKPPKVQEK CQLEINFNTL 360
  361 QTKLRLSNRP AFMPSEGRMV SDINNGWQHL EQAEKGYEEW LLNEIRRLER LDHLAEKFRQ 420
  421 KASIHEAWTD GKEAMLKHRD YETATLSDIK ALIRKHEAFE SDLAAHQDRV EQIAAIAQEL 480
  481 NELDYYDSHN VNTRCQKICD QWDNLGSLTH SRREALEKTE KQLETIDQLH LEYAKRAAPF 540
  541 NNWMESAMED LQDMFIVHTI EEIEGLISAH DQFKSTLPDA DREREAILAI HKEAQRIAES 600
  601 NHIKLSGSNP YTSVTPQIIN SKWEKVQQLV PKRDHALLEE QSKQQSNEHL RRQFASQANM 660
  661 VGPWIQTKME EIGRISIEMN GTLEDQLSHL KQYERSIVDY KPNLDLLEQQ HQLIQEALIF 720
  721 DNKHTNYTME HLRVGWEQLL TTIARTINEV ENQILTRDAK GISQEQMQEF RASFNHFDKD 780
  781 HGGALGPEEF KACLISLGYD VENDRQGDAE FNRIMSVVDP NHSGLVTFQA FIDFMSRETT 840
  841 DTDTADQVIA SFKVLAGDKN FITAEELRRE LPPDQAEYCI ARMAPYQGPD AAPGALDYKS 900
  901 FSTALYGESD L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ACTN4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: