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Protein Overview: gi|37623931

General Information:
Name(s) found: gi|37623931 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|37623931|gb|AAP80789.2| cardiac titin N2BA isoform [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 3410 amino acids

    Gene Ontology:
    Cellular Component: striated muscle thin filament [UNKNOWN]
    Z disc [UNKNOWN]
    cytosol [UNKNOWN]
    I band [UNKNOWN][IDA]
    M band [UNKNOWN]
    A band [UNKNOWN]
    extracellular region [UNKNOWN]
    sarcomere [UNKNOWN]
    condensed nuclear chromosome [UNKNOWN]
    myofibril [IDA]
    Biological Process: regulation of protein kinase activity [UNKNOWN]
    mitotic chromosome condensation [UNKNOWN]
    skeletal muscle thin filament assembly [UNKNOWN]
    sarcomere organization [UNKNOWN][IDA]
    forward locomotion [UNKNOWN]
    protein amino acid phosphorylation [IEA]
    cardiac muscle fiber development [UNKNOWN]
    adult heart development [UNKNOWN]
    heart morphogenesis [UNKNOWN]
    in utero embryonic development [UNKNOWN]
    muscle contraction [UNKNOWN]
    response to calcium ion [UNKNOWN]
    regulation of catalytic activity [UNKNOWN]
    striated muscle cell development [UNKNOWN]
    skeletal muscle thick filament assembly [UNKNOWN]
    cardiac myofibril assembly [UNKNOWN]
    cardiac muscle tissue morphogenesis [UNKNOWN]
    Molecular Function: actin filament binding [UNKNOWN]
    ATP binding [IEA]
    protein tyrosine kinase activity [IEA]
    calmodulin binding [UNKNOWN]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN]
    structural constituent of muscle [UNKNOWN]
    calcium ion binding [UNKNOWN]
    alpha-actinin binding [UNKNOWN]
    protein serine/threonine kinase activity [UNKNOWN][IEA]
    protein self-association [UNKNOWN]
    telethonin binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQCQVAGTPE ITVSWFKGDT KLRSTPEYRT YFTNNVATLV FNKVGINDSG EYTCVAENSI  60
   61 GTAASKTVFR IQERQLPPSF ARQLKDIEQT VGLPVTLTCR LNGSAPIHVC WYRDGVLLRD 120
  121 DENLQMSFVD NVATLKILQT DLSHSGQYSC SASNPLGTAS STARLTAREP KKSPFFDIKP 180
  181 VSIDVIAGES ADFECHVTGA QPMRVTWSKD NKEIRPGGNY TITCVGNTPH LRILKVGKGD 240
  241 SGQYTCQATN DVGKDMCSAQ LSVKEPPKFI KKLDTSKVAK QGESIQLECK ISGSPEIKVV 300
  301 WFRNDSELHE SWKYNMSFVN SVALLTINEA SVEDTGDYIC EAHNGVGHAS CSTALKVKAP 360
  361 PVFTQKPPPV GALKGSDVIL QCEISGTPPF EVVWVKDRKQ VRSSKKFKVT SKNFDTSLHI 420
  421 FNLEAPDIGE YHCKATNEVG SDTCACTVKF KEPPRFVKKL SDVSTLIGDP VELQAVVEGF 480
  481 QPISVVWLKD KGEVIRESEN VRISFVDNIA TLQLGSPEAS HSGKYVCQIK NDAGMRECSA 540
  541 LLTVLEPARI VEKPEPMTVT TGNPFTLECV VAGTPELSAK WLKDGRELSS GSRHHITFVR 600
  601 NLASLKIPSA EMNDKGLYSF EVENSVGKSS CTVSVHVSDR VVPPSFIRKL KDTTATLGAS 660
  661 VVLECRVSGS APISVGWFLD GNEIISSPKC QPSFADNVCT LTLSSLEPSD TGAYTCVAAN 720
  721 VAGQDESSAL LTVQEPPSFE QTPDSVEVLP GMSLTFTSVF RGTPPFKVKW FKGSRELESG 780
  781 EACTISLEDF VTELELLEVE PLQSGDYSCL VTNDAGSASC TTHLFVKEPA TFVKRLADTS 840
  841 VETGSPIVLE ATYSGTPPIA VSWLKNEYPL SQSPNCGITT TERSSILEIL ESTIEDYAQY 900
  901 ACLIENEAGQ DICEALVSVL EPPYFIEPLE HVEAAIGEPT TLQCKVDGTP EIRISWYKEH 960
  961 TKLRSAPAYK MQFKNNVASL VINKVDHSDV GEYTCKAENS VGAVASSAVL VIKERKLPPS1020
 1021 FARKLKDVHE TLGFPVAFEC RINGSEPLQV SWYKDGQLLK DDSNLQMSFV HHVATLQILQ1080
 1081 TDQSHVGQYN CSASNPLGTA SSSAKLILSE HEVPPFFDLK PVSVDLALGE SGSFKCHVTG1140
 1141 TAPIKITWAK DNREIRPGGN YKMTLVENTA TLTVLKVAKG DAGQYTCYAS NVAGKDSCSA1200
 1201 QLGVQEPPRF IKKLDQSRIV KQDEYTRYEC KIGGSPEIKV LWYKDEVEIQ ESSKFRMSFE1260
 1261 DSVAILEMHN LSVEDSGDYT CEARNAAGSA SSSTSLKVKE PPVFRKKPFP VETLKGADVH1320
 1321 LECELQGTPP FQVSWYKDKR ELRSGKKYKI MSENLLTSIH ILNVDTADIG EYQCKATNDV1380
 1381 GSDTCVGSVT LKAPPQFVKK LSDVSTIIGK EVQLQTTIEG AEPISVAWFK DKGEIVRESD1440
 1441 NIWISHSENV ATLHFSRAEP ANAGKYTCQI KNDAGVQECY ATLSVLEPAT IVEKPESIKV1500
 1501 TTGDTCTLEC MVSGTPELST KWFKDGKELT GDSKYKISFF NKVSGLKIIS VAPGDSGVYS1560
 1561 FEVQNPVGKD SCTVSIQVSD RIIPPSFTRK LKETNGLSGS SVVMECKVFG SPPISVLWLH1620
 1621 DGNAISSGRK YQTTLTDNTC ALTVNMLEDA DAGDYTCIAT NVAGSDECSA PLTVREPPSF1680
 1681 VQKPDPMDVL TGSNVTFTSI VKGTPPFTVS WFKGSSELVP GARCNVSLQD SVAELELFDV1740
 1741 DTSQSGDYTC IVSNEAGRAS CTTQLFVKAP AIFVKRLNDY SIEKGKPLIL EGTFSGTPPI1800
 1801 SVTWKKNGVN VTASQRCNIT TTEKSAILEI LSSTVEDSGQ YNCYIENASG KDSCSAQILI1860
 1861 LEPPYFVKQL EPLKVTVGDS ASLQCQLAGT PEIGVSWYKG DTKLRPTTTC KMHFKNNVAT1920
 1921 LVFTQVDSND SGEYICRAEN SVGEVSSSTF LTVQEQKLPP SFSRQLRDVQ ETVGLPVVFE1980
 1981 CAVSGSEPIS VSWYKDGKPL KDSPNVQTSF LDNIATLNIF KTDRSLAGQY SCTVTNPIGS2040
 2041 ASSSAKLILT EGKNPPFFDI PLAPVDAVVG ESADLECHVT GTQPIKVTWA KDNREIRSGG2100
 2101 NYQISYLENS AHLTIVKVDK GDSGQYTCYA INEVGKDSCT AQLNIKERLT PPSFTKKLSE2160
 2161 TIEETEGNSF KLEGRVAGSQ PITIAWYKNN VEIHPTSNCE ITFKNNALLL QVKKASMADA2220
 2221 GLYTCKATND AGSALCTSSI VIREPKKPPV FDQHLTPVTA SEGDFLQLSC HVQGSEPIRI2280
 2281 QWLRAGREIK PSDRCSFSFA SGTAVLELKD TAKADSGDYV CKASNVAGSD TSKCKVTIKE2340
 2341 KPAAAPAAKK AAVDGKLFFV SEPQSIRVVE KTTATFIAKV GGDPIPNVKW TKGKWRQLNQ2400
 2401 GGRILIHQKG DESKLEIRDT TKTDSGLYRC VAFNKHGEIE SNVNLQVDER KKQEKIEGDL2460
 2461 RAMLKKTPAL KKGSGEEEEI DIMELLKNVD PKEYEKYARM YGITDFRGLL QAFELLKQSQ2520
 2521 EEETHRLEIE ELEKSERDEK EFEELVSFIQ QRLTQTEPVT LIKDIENQTV LKDNDAIFEI2580
 2581 DIKINYPEIK LSWYKGTEKL EPSNKYEITI NGDRHTLRVR NCQLKDQGNY RLVCGPHIAS2640
 2641 AKLTVIEPAW ERHLQDVTLK EGQTCTMTCQ FSVPNVKSEW FRNGRVLKPQ GRVKTEVEHK2700
 2701 VHKLTIADVR AEDQGRYTCK HEDLETSAEL RIEAEPIQFT KRIQNIVVSE HQSATFECEV2760
 2761 SFDDAIVTWY KGPTELTESQ KYNFRNDGRC HYMTIHNVTP DDEGVYSVIA RLEPRGEARS2820
 2821 TAELYLTTKE IKLEMKPPDI PDSRVPIPTM PIRAVPPEEI PPAVAPSIPL LLPLPEEKKP2880
 2881 PAKRIEVTKK GVKKDTKKVV AKPKEEAPPP PPVPEVAKKP PPPTPMIPAK PSEIIDVSSK2940
 2941 AEEVKITTIT RKKEIHKEKE AVYERKEAVY EKKVLIEPWE EPYEELETEP YTEPYEEPYY3000
 3001 EEPDEDYEEI KVEAKKEVHE EWEEDYEEGQ EYYEREEGYD EGEEEWEEIY HEREIIQVQK3060
 3061 EVHEDLHEKK IPAKVPEKKV PPPKVPEAPK KPAPEEKTAV PVAKKKEAPP PKVPEVPKKP3120
 3121 VPEEKAPVPV PKKVEPPPAK VPEVPKKPVP EKKVPAPTPK KVEAPPAKAP EVPPKEVTPE3180
 3181 KKVPVVPPKK PEAPPPKVPT AEKKVRKLLP EPKPQPKEEV VLKSVLRKRP EEEEPKVEPK3240
 3241 KVEKVKKPEE PPPPPKAVEV EAPPEPKPKE RKVPEPTKVP EIKPAIPLPG PEPKPKPEPE3300
 3301 VKTMKAPPIE PAPTPIAAPV TAPVVGKKAE AKPKDEAAKP KGPIKGVAKK TPSPIEAERK3360
 3361 KLRPGSGGEK PPDEAPFTYQ LKAVPLKFVK EIKDIVLTEA ESVGSSAIFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle