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Protein Overview: PLCD5_ARATH

General Information:
Name(s) found: PLCD5_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75306039|sp|Q944C2.2|PLCD5_ARATH RecName: Full=Phosphoinositide phospholipase C 5; AltName: Full=Phosphoinositide phospholipase PLC5; Short=PI-PLC5; Short=AtPLC5; Short=AtPLCx [NCBI NR]
  • gi|34098919|gb|AAQ56842.1| At5g58690 [Arabidopsis thaliana] [NCBI NR]
  • gi|22327954|ref|NP_200677.2| phosphoinositide-specific phospholipase C family protein [Arabidopsis thaliana] [NCBI NR]
  • gi|19855030|gb|AAL30748.2|AF434167_1 phosphoinositide-specific phospholipase C [Arabidopsis thaliana] [NCBI NR]
  • gi|17065210|gb|AAL32759.1| phosphoinositide-specific phospholipase C-line [Arabidopsis thaliana] [NCBI NR]
  • Phosphoinositide phospholipase C 5 OS=Arabidopsis thaliana GN=PLC5 PE=2 SV=2 [Swiss-Prot]
  • At5g58690 [Arabidopsis thaliana]gi|19855030|gb|AAL30748.2| phosphoinositide-specific phospholipase C [Arabidopsis thaliana]gi|17065210|gb|AAL32759.1| phosphoinositide-specific phospholipase C-line [Arabidopsis thaliana]gi|22327954|ref|NP_200677.2| phos [nrdb_11152004_Chlamydomonas]
  • | Symbols: | phosphoinositide-specific phospholipase C family protein | chr5:23726902-23729256 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • phosphoinositide phospholipase C/ phospholipase C [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • phosphoinositide-specific phospholipase C-line [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At5g58690 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • phosphoinositide-specific phospholipase C [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATPLC5, PLC5 | phosphatidylinositol-speciwc phospholipase C5 | chr5:23709676-23712030 REVERSE LENGTH=578 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 578 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: intracellular signaling pathway [IEA]
    signal transduction [IEA][ISS]
    lipid metabolic process [IEA]
    Molecular Function: phosphoinositide phospholipase C activity [IEA]
    phospholipase C activity [IEA][ISS]
    calcium ion binding [IEA]
    phosphoric diester hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRDMGSYKM GLCCSDKLRM NRGAPPQDVV TAFVEYTEGR SHMTAEQLCR FLVEVQDETE  60
   61 VLVSDAEKII ERITCERHHI TKFLRHTLNL DDFFSFLFSD DLNHPIDSKV HQDMASPLSH 120
  121 YFIYTSHNSY LTGNQINSEC SDVPLIKALK RGVRALELDM WPNSTKDDIL VLHGWAWTPP 180
  181 VELVKCLRSI KEHAFYASAY PVILTLEDHL TPDLQAKAAE MMKEIFMDMV YFPEAGGLKE 240
  241 FPSPEDLKYK IVISTKPPKG SLRKDKDSES DASGKASSDV SADDEKTEEE TSEAKNEEDG 300
  301 FDQESSNLDF LTYSRLITIP SGNAKNGLKE ALTIDNGGVR RLSLREQKFK KATEMYGTEV 360
  361 IKFTQKNLLR IYPKATRVNS SNYRPYNGWM YGAQMVAFNM QGYGRALWMM HGMFRGNGGC 420
  421 GYVKKPDFMM NNNLSGEVFN PKAKLPIKKT LKVKVYMGKG WDSGFQRTCF NTWSSPNFYT 480
  481 RVGITGVRGD KVMKKTKKEQ KTWEPFWNEE FEFQLTVPEL ALLRIEVHDY NMPEKDDFSG 540
  541 QTCLPVSELR QGIRSVPLYD RKGERLVSVT LLMRFHFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..578] PSI-BLAST 164.0 Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phospholipase C activity
    		•  1.68837208308012 bayes_pls_golite062009
  • hydrolase activity
    		•  1.21781019708396 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  1.06268977958067 bayes_pls_golite062009
  • catalytic activity
    		•  1.05111689766686 bayes_pls_golite062009
  • phospholipase activity
    		•  0.87334512532594 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.539550637107889 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.49944935937406 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.486374653947972 bayes_pls_golite062009
  • lipase activity
    		•  0.46273678058621 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.273676921589143 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.266794283648202 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0724768101463518 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle