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Protein Overview: CYSG_PSEAE

General Information:
Name(s) found: CYSG_PSEAE [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Siroheme synthase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=cysG PE=3 SV=1 [Swiss-Prot]
    • Organism: Pseudomonas aeruginosa PAO1
    Length: 465 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFLPLFHSL QGRLALVVGG GEVALRKARL LADAGARLRV VAPQIHIELR HLVEQGGGEL  60
   61 LERDYQDGDQ PGCALIIAAT DDEPLNAEVS RAANARGIPV NVVDAPALCS VIFPAIVDRS 120
  121 PLVVAVSSGG DAPVLARLIR AKLETWIPST YGQLAGLASR FRHRVKELLP DLQQRRVFWE 180
  181 NLFQGEIAER VLAGRPAEAE RLLEEHLAGG LAHIATGEVY LVGAGPGDPD LLTFRALRLM 240
  241 QQADVVLYDR LVAPSILELC RRDAERLYVG KRRAEHAVPQ DRINRLLVEL ASQGKRVLRL 300
  301 KGGDPFIFGR GGEEIDELAA HGIPFQVVPG ITAASGCAAY AGIPLTHRDH AQSVRFVTGH 360
  361 LKDGTTDLPW QDLVAPGQTL VFYMGLVGLP VICEQLVAHG RSAQTPAALI QQGTTAQQRV 420
  421 FTGTLENLPQ LVAEHEVHAP TLVIVGEVVQ LRDKLAWFEG AREDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 126.0 Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrin-III C-methyltransferase activity
    		•  3.573271502205 bayes_pls_golite062009
  • C-methyltransferase activity
    		•  3.35393353163232 bayes_pls_golite062009
  • precorrin-4 C11-methyltransferase activity
    		•  2.18371138649366 bayes_pls_golite062009
  • catalytic activity
    		•  1.48349578618275 bayes_pls_golite062009
  • transferase activity
    		•  0.912524944496351 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.431791521097299 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.424918406685891 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.28351517300952 bayes_pls_golite062009
  • uroporphyrinogen-III synthase activity
    		•  0.00871858903098705 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle