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Protein Overview: FPG_GEOSL

General Information:
Name(s) found: FPG_GEOSL [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Formamidopyrimidine-DNA glycosylase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=mutM PE=3 SV=3 [Swiss-Prot]
    • Organism: Geobacter sulfurreducens PCA
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [ISSLink to PubMed article]
    Molecular Function: oxidized purine base lesion DNA N-glycosylase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPELPEVETT LRGIAPHVTG RRVTAVTARA AKLRLPIPPE LGERLTGRVI ERVERRAKYL  60
   61 LLRCGDGTAI IHLGMTGTLR VAPAGSPPGK YDHLDLVLDD GRTLRFRDPR KFGLVLWTGS 120
  121 DPLAHPLLAQ LGPEPFPPLF NGSYLFSRSR KRNAAIKLLL MDNRIVVGVG NIYANEALFR 180
  181 ARIHPERAAG SLSEEDCATL ATAVGDVLRD AIAEGDTTLH EFIATEVPSG YFRINPAVYG 240
  241 QTGKPCTVCG TPIARIRLGN RSTWFCPVCQ K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 105.0 DNA repair protein MutM (Fpg)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA N-glycosylase activity
    		•  4.06377793944255 bayes_pls_golite062009
  • oxidized base lesion DNA N-glycosylase activity
    		•  3.68895100180378 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  3.63831813037192 bayes_pls_golite062009
  • oxidized purine base lesion DNA N-glycosylase activity
    		•  3.50273405950314 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  3.32722481172627 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  2.59048389792519 bayes_pls_golite062009
  • hydrolase activity
    		•  1.74627738237592 bayes_pls_golite062009
  • binding
    		•  1.7313696856499 bayes_pls_golite062009
  • DNA binding
    		•  1.22619720972604 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.17199530230795 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16376707327858 bayes_pls_golite062009
  • protein binding
    		•  1.14219782236887 bayes_pls_golite062009
  • transcription factor activity
    		•  0.472763834470731 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009
  • lyase activity
    		•  0.0836281676510939 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle