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Protein Overview: TYSY_COXBU

General Information:
Name(s) found: TYSY_COXBU [Swiss-Prot]
Description(s) found:
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  • gi|29654838|ref|NP_820530.1| thymidylate synthase [Coxiella burnetii RSA 493] [NCBI NR]
  • gi|29542106|gb|AAO91044.1| thymidylate synthase [Coxiella burnetii RSA 493] [NCBI NR]
  • Thymidylate synthase OS=Coxiella burnetii (strain RSA 493 / Nine Mile phase I) GN=thyA PE=3 SV=1 [Swiss-Prot]
  • thymidylate synthase [Coxiella burnetii RSA 493]gi|29542106|gb|AAO91044.1| thymidylate synthase [Coxiella burnetii RSA 493] [nrdb_11152004_Chlamydomonas]
  • thymidylate synthase [Coxiella burnetii RSA 493] [nr-271106-contam.fasta]
    • Organism: Coxiella burnetii RSA 493
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: 2'-deoxyribonucleotide biosynthetic process [ISSLink to PubMed article]
    Molecular Function: thymidylate synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEYLNFLQF ILDHGVAKTD RTGIGTKSVF GYEMRFNLRE GFPLVTTKKI HLKSVIYELL  60
   61 WFLRGDTNIQ FLNDNGVTIW DEWADENGDL GPIYGKQWRR WHCPDGRTVD QMQRLIREIK 120
  121 TNPDSRRLIV SAWNVGELDQ MALPPCHLLF QFYVADGFLS CKLTQRSADA FLGVPFNIAS 180
  181 YSLLTHLIAR QCNLKAGEFI WSGGDCHIYN THQDQVSTQL SREPRALPQL IINRDPSSLY 240
  241 DYNFNDFSIV NYHPHPAIKA PVAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] PSI-BLAST 133.0 Thymidylate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thymidylate synthase activity
    		•  6.6988475347328 bayes_pls_golite062009
  • 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
    		•  6.29181090719132 bayes_pls_golite062009
  • binding
    		•  1.89072001556053 bayes_pls_golite062009
  • catalytic activity
    		•  1.73427871128495 bayes_pls_golite062009
  • transferase activity
    		•  1.72626940963556 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.927096828883487 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.91282507161672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle