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Protein Overview: PUR4_SHEON

General Information:
Name(s) found: PUR4_SHEON [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Phosphoribosylformylglycinamidine synthase OS=Shewanella oneidensis (strain MR-1) GN=purL PE=3 SV=1 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 1293 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: purine ribonucleotide biosynthetic process [ISSLink to PubMed article]
    Molecular Function: phosphoribosylformylglycinamidine synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIIRGAPAL STFRVQKLME ACVSAALPVR QIYAEYVHLA DLSELLKPTE REQLEKILTY  60
   61 GPAIEAHTPQ GSLLFVTPRP GTISPWSSKA TDIAHNCGLG KVKRLERGIA YYVESDTLTA 120
  121 EQQRTLQGLL HDRMVEVVLN DFAKADVLFK RTEPAPFKSV NVLAEGRRAL EVANVEMGLA 180
  181 LAEDEIDYLV ENFVRLNRNP NDIELMMFAQ ANSEHCRHKI FNADWTIDGK AQPKSLFKMI 240
  241 KNTFEVTPDH VLSAYKDNAA VMEGSVAGRF FPDPNGVYSY HTEPMHVLMK VETHNHPTAI 300
  301 SPYPGAATGS GGEIRDEGAT GRGSKPKAGL TGFSVSNLKI PGFVQPWEGN YGKPDRIVSA 360
  361 LDIMTEGPLG GAAFNNEFGR PALLGYFRTY EQEVSSHNGV EMRGYHKPIM LAGGLGNIRE 420
  421 EHVQKGEITV GAKLIVLGGP AMNIGLGGGA ASSMASGQSS EDLDFASVQR ENPEMERRCQ 480
  481 EVIDRCWQLG DKNPIQFIHD VGAGGLSNAF PELVNDGDRG GIFNLRNVPS DEPGMSPLEI 540
  541 WCNESQERYV LSVAAEDLPL FTAICERERA PFAVVGEAIQ EQHLTLADSH FDNNPIDLPL 600
  601 EVLLGKAPKM SRNVVSAKAV SPALEQSQID VKDAVKRVLS LPTVADKTFL ITIGDRTVTG 660
  661 LVNRDQMVGP WQVPVADCAV TAASFDTYAG EAMSLGERTP LALLDFGASA RMAVAESIMN 720
  721 IAGADIGSFK RIKLSANWMS AAGHPGEDAG LYEAVKAVGE ELCPELSLTI PVGKDSMSMK 780
  781 TAWQQDGVNK TVTSPMSLVI TAFGVVQDIR NTVTPELRSD KGETSLLLVD LGAGQNRLGG 840
  841 SCLAQVYGEL GDVAPDLDDA ALLRGFFETM QKLVANKLVI AYHDRSDGGL FTTLVEMAFA 900
  901 GNIGLDIDVE DLQGTDLERL FNEELGAVLQ VSRDNAAKIA AQFAIAGVPC HVIGTLADDQ 960
  961 CITIKDGARE IFSDTRVALR TVWSETTYRM QAMRDNPACA LEEFKLKQDE TDLGLTVNLS1020
 1021 FDPSEDVAAP YILKGAAPKM AILREQGVNS HVEMAAAFDR AGFESRDVHM SDILSGRISL1080
 1081 EEFQGLVACG GFSYGDVLGA GEGWAKSILF NERARNEFSR FFERDSSFAL GVCNGCQMLS1140
 1141 NLKEIIPGSE HWPRFVRNRS ERFEARFSLV EVQQSPSLFF QGMAGSRMPI AVSHGEGHAE1200
 1201 FASAQALALA EASGTIALRF VNGKGEIATQ YPQNPNGSPN GLTGICTTDG RVTLMMPHPE1260
 1261 RVFRTVANSW HPDNWGEDSP WMRMFRNARV NLG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1293] PSI-BLAST 1000.0 Structure of Formylglycinamide synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoribosylformylglycinamidine cyclo-ligase activity
    		•  3.04322905277855 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.97429034492683 bayes_pls_golite062009
  • catalytic activity
    		•  2.42746873085914 bayes_pls_golite062009
  • cyclo-ligase activity
    		•  2.40623349460413 bayes_pls_golite062009
  • phosphoribosylformylglycinamidine synthase activity
    		•  2.05243869055537 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  1.74828881793189 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  1.74029540439985 bayes_pls_golite062009
  • ligase activity
    		•  1.57503501977169 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  1.2570804600775 bayes_pls_golite062009
  • binding
    		•  1.25028632595227 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.78656048097577 bayes_pls_golite062009
  • protein binding
    		•  0.277844441308003 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.12569720972861 bayes_pls_golite062009
  • kinase activity
    		•  0.118160290398407 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle