YRC Public Data Repository - Protein Structure Prediction

Protein:	PUR4_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	1293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUR4_SHEON.

Description	E-value	Query Range	Subject Range
gi\|125619740, gi... - gi\|75831918\|ref\|ZP_00761177.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas... gi\|146315234, gi... - gi\|75826192\|ref\|ZP_00755627.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas... PUR4_VIBCH - Phosphoribosylformylglycinamidine synthase OS=Vibrio cholerae GN=purL PE=3 SV=1 gi\|121550061, gi... - gi\|121585698\|ref\|ZP_01675493.1\| phosphoribosylformylglycinamidine synthase [Vibrio cholerae 2740-80]... gi\|229371197, gi... - gi\|229608542\|ref\|YP_002879190.1\| phosphoribosylformylglycinamidine synthase synthetase subunit/phosp... gi\|124117863, gi... - gi\|153224103\|ref\|ZP_01954227.1\| phosphoribosylformylglycinamidine synthase [Vibrio cholerae MAK 757]... gi\|229517927, gi... - gi\|229517927\|ref\|ZP_04407371.1\| phosphoribosylformylglycinamidine synthase synthetase subunit/phosph... PUR4_VIBCH - Phosphoribosylformylglycinamidine synthase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El To... gi\|153819005, gi... - gi\|153819005\|ref\|ZP_01971672.1\| phosphoribosylformylglycinamidine synthase [Vibrio cholerae NCTC 845... gi\|229357746, gi... - gi\|229505523\|ref\|ZP_04395033.1\| phosphoribosylformylglycinamidine synthase synthetase subunit/phosph... gi\|229510807, gi... - gi\|229510807\|ref\|ZP_04400286.1\| phosphoribosylformylglycinamidine synthase synthetase subunit/phosph... gi\|227081045, gi... - gi\|227081045\|ref\|YP_002809596.1\| phosphoribosylformylglycinamidine synthase [Vibrio cholerae M66-2],...	1332.0	[0..1]	[1293..1]
gi\|121629408, gi... - gi\|75815489\|ref\|ZP_00745995.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1332.0	[0..1]	[1293..1]
lcl\|NC_016856.1_... - [gene=purG] [protein=phosphoribosylformylglycinamidine synthase] [protein_id=YP_005238672.1] [locati... PUR4_SALTY - Phosphoribosylformylglycinamidine synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7... PUR4_SALTY - Phosphoribosylformylglycinamidine synthase OS=Salmonella typhimurium GN=purL PE=1 SV=3 PUR4_SALTY - Phosphoribosylformylglycinamidine synthase OS=Salmonella typhimurium GN=purL PE=1 SV=3 gi\|205329118, gi... - gi\|205357853\|ref\|ZP_02573792.2\| phosphoribosylformylglycinamidine synthase [Salmonella enterica subs...	1331.0	[0..1]	[1293..2]
gi\|224467421, gi... - gi\|224582894\|ref\|YP_002636692.1\| phosphoribosylformylglycinamidine synthase [Salmonella enterica sub... PUR4_SALCH - Phosphoribosylformylglycinamidine synthase OS=Salmonella choleraesuis (strain SC-B67) GN=purL PE=3 S... PUR4_SALCH - Phosphoribosylformylglycinamidine synthase OS=Salmonella choleraesuis GN=purL PE=3 SV=3 PUR4_SALCH - Phosphoribosylformylglycinamidine synthase OS=Salmonella choleraesuis GN=purL PE=3 SV=3	1330.0	[0..1]	[1293..2]
PUR4_SHESM - Phosphoribosylformylglycinamidine synthase OS=Shewanella sp. (strain MR-4) GN=purL PE=3 SV=1	1329.0	[0..1]	[1293..1]
gi\|197361493, gi... - gi\|197361493\|ref\|YP_002141129.1\| phosphoribosylformylglycinamidine synthase [Salmonella enterica sub... PUR4_SALPA - Phosphoribosylformylglycinamidine synthase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=... PUR4_SALPA - Phosphoribosylformylglycinamidine synthase OS=Salmonella paratyphi A GN=purL PE=3 SV=3	1328.0	[0..1]	[1293..2]
gi\|78686232, gi\|... - gi\|78686232\|ref\|ZP_00851002.1\| Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobact...	1328.0	[0..1]	[1293..1]
PUR4_SHESR - Phosphoribosylformylglycinamidine synthase OS=Shewanella sp. (strain MR-7) GN=purL PE=3 SV=1	1327.0	[0..1]	[1293..1]
gi\|194537878, gi... - gi\|75819598\|ref\|ZP_00749670.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1327.0	[0..1]	[1293..1]
gi\|75855043, gi\|... - gi\|75855043\|ref\|ZP_00762707.1\| COG0046: Phosphoribosylformylglycinamidine (FGAM) synthase, synthetas...	1327.0	[0..1]	[1293..1]

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Predicted Domain #1

Region A:
Residues: [1-1293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIIRGAPAL STFRVQKLME ACVSAALPVR QIYAEYVHLA DLSELLKPTE REQLEKILTY  60
   61 GPAIEAHTPQ GSLLFVTPRP GTISPWSSKA TDIAHNCGLG KVKRLERGIA YYVESDTLTA 120
  121 EQQRTLQGLL HDRMVEVVLN DFAKADVLFK RTEPAPFKSV NVLAEGRRAL EVANVEMGLA 180
  181 LAEDEIDYLV ENFVRLNRNP NDIELMMFAQ ANSEHCRHKI FNADWTIDGK AQPKSLFKMI 240
  241 KNTFEVTPDH VLSAYKDNAA VMEGSVAGRF FPDPNGVYSY HTEPMHVLMK VETHNHPTAI 300
  301 SPYPGAATGS GGEIRDEGAT GRGSKPKAGL TGFSVSNLKI PGFVQPWEGN YGKPDRIVSA 360
  361 LDIMTEGPLG GAAFNNEFGR PALLGYFRTY EQEVSSHNGV EMRGYHKPIM LAGGLGNIRE 420
  421 EHVQKGEITV GAKLIVLGGP AMNIGLGGGA ASSMASGQSS EDLDFASVQR ENPEMERRCQ 480
  481 EVIDRCWQLG DKNPIQFIHD VGAGGLSNAF PELVNDGDRG GIFNLRNVPS DEPGMSPLEI 540
  541 WCNESQERYV LSVAAEDLPL FTAICERERA PFAVVGEAIQ EQHLTLADSH FDNNPIDLPL 600
  601 EVLLGKAPKM SRNVVSAKAV SPALEQSQID VKDAVKRVLS LPTVADKTFL ITIGDRTVTG 660
  661 LVNRDQMVGP WQVPVADCAV TAASFDTYAG EAMSLGERTP LALLDFGASA RMAVAESIMN 720
  721 IAGADIGSFK RIKLSANWMS AAGHPGEDAG LYEAVKAVGE ELCPELSLTI PVGKDSMSMK 780
  781 TAWQQDGVNK TVTSPMSLVI TAFGVVQDIR NTVTPELRSD KGETSLLLVD LGAGQNRLGG 840
  841 SCLAQVYGEL GDVAPDLDDA ALLRGFFETM QKLVANKLVI AYHDRSDGGL FTTLVEMAFA 900
  901 GNIGLDIDVE DLQGTDLERL FNEELGAVLQ VSRDNAAKIA AQFAIAGVPC HVIGTLADDQ 960
  961 CITIKDGARE IFSDTRVALR TVWSETTYRM QAMRDNPACA LEEFKLKQDE TDLGLTVNLS1020
 1021 FDPSEDVAAP YILKGAAPKM AILREQGVNS HVEMAAAFDR AGFESRDVHM SDILSGRISL1080
 1081 EEFQGLVACG GFSYGDVLGA GEGWAKSILF NERARNEFSR FFERDSSFAL GVCNGCQMLS1140
 1141 NLKEIIPGSE HWPRFVRNRS ERFEARFSLV EVQQSPSLFF QGMAGSRMPI AVSHGEGHAE1200
 1201 FASAQALALA EASGTIALRF VNGKGEIATQ YPQNPNGSPN GLTGICTTDG RVTLMMPHPE1260
 1261 RVFRTVANSW HPDNWGEDSP WMRMFRNARV NLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1t3tA
Description:	Structure of Formylglycinamide synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosylformylglycinamidine cyclo-ligase activity	3.04322905277855	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.97429034492683	bayes_pls_golite062009
catalytic activity	2.42746873085914	bayes_pls_golite062009
cyclo-ligase activity	2.40623349460413	bayes_pls_golite062009
phosphoribosylformylglycinamidine synthase activity	2.05243869055537	bayes_pls_golite062009
carbamoyl-phosphate synthase activity	1.74828881793189	bayes_pls_golite062009
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	1.74029540439985	bayes_pls_golite062009
ligase activity	1.57503501977169	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1.2570804600775	bayes_pls_golite062009
binding	1.25028632595227	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.78656048097577	bayes_pls_golite062009
protein binding	0.277844441308003	bayes_pls_golite062009
nucleic acid binding	0.12569720972861	bayes_pls_golite062009
kinase activity	0.118160290398407	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: