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Protein Overview: HIS7_SHEON

General Information:
Name(s) found: HIS7_SHEON [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Histidine biosynthesis bifunctional protein HisB OS=Shewanella oneidensis (strain MR-1) GN=hisB PE=3 SV=1 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: histidine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: imidazoleglycerol-phosphate dehydratase activity [ISSLink to PubMed article]
    histidinol-phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPVFTPNVA QKILFIDRDG TLIEEPVTDK QVDNLAKLVF EPQVIPALLR LQKAGFRLVM  60
   61 VSNQDGLGTP SFPQEDFDAP HNMMMQILSS QGVKFEDVLI CPHFNDENCS CRKPKLGLVK 120
  121 DFLTQGFIDF TQSAVIGDRH TDVELGNAMG IISFQYQRGS LGWNAIADAL LNKGRSATVV 180
  181 RTTKETDIRV TVDLDNASKG TINTGIGFFD HMLDQIATHG NFKMEVNVDG DLEIDDHHSV 240
  241 EDTALAIGDA LRQALGDKRG IARFGFSLPM DEAKGECLLD LSGRPFIKFA AQFEREKVGE 300
  301 MATEMVPHFF RSFADGLRCT LHVAAEGDND HHKVEALFKV LGRALRQAVK VEGDVLPSSK 360
  361 GVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..171] PSI-BLAST 26.522879 No description for 2fprA was found.
    2 View Details [172..363] PSI-BLAST 83.39794 X-Ray Structure of imidazoleglycerol-phosphate dehydratase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • binding
    		•  0.403742083069476 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.311168802206529 bayes_pls_golite062009
  • imidazoleglycerol-phosphate dehydratase activity
    		•  0.194869838584556 bayes_pls_golite062009
  • phosphatase activity
    		•  0.159899259988948 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.103902756538853 bayes_pls_golite062009
  • hydrolase activity
    		•  0.01837003348146 bayes_pls_golite062009
    2
    Term Confidence Notes
  • imidazoleglycerol-phosphate dehydratase activity
    		•  1.6337728630325 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.89499871627607 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • binding
    		•  0.806477220933291 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.417420176258912 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.325699575011026 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.212099606954236 bayes_pls_golite062009
  • structural molecule activity
    		•  2.19428886088058E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle