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Protein Overview: gi|24372616, gi|...

General Information:
Name(s) found: gi|24372616 [NCBI NR]
gi|24346645 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|24372616|ref|NP_716658.1| B12-dependent methionine synthase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24346645|gb|AAN54103.1|AE015547_9 5-methyltetrahydrofolate--homocysteine methyltransferase [Shewanella oneidensis MR-1] [NCBI NR]
    • Organism: Shewanella oneidensis MR-1
    Length: 1244 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: methionine synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAISPNRASH TLADIRNQLS TRILILDGAM GTMIQGYKLE EADYRGERFK DWHTDVKGNN  60
   61 DLLVLTQPHI IKQIHTDYLL AGADIIETNT FNATTIAMAD YDMQSLSAEI NREGARLARE 120
  121 ACDAIEQATG KPRYVAGVLG PTNRTCSISP DVNDPGFRNI HFDELVTAYC ESTRALIEGG 180
  181 ADIIMVETIF DTLNAKAALF AIETVFDELF GANSPARLPV MISGTITDAS GRTLTGQTTE 240
  241 AFYNSLRHIK PLSIGLNCAL GPKELRPYVE ELSRIAECYV SAHPNAGLPN EFGGYDETPE 300
  301 DMAKVIQEWA REGMLNIIGG CCGSTPEHIK VIREAVEQFA PRVLPEIPVA CRLAGLEPLT 360
  361 IDAQTLFVNV GERTNVTGSA KFLKLIKEGK FEQALDVARE QVESGAQIID INMDEGMLDG 420
  421 VEIMHKFLNL IASEPDISRV PIMIDSSKWE VIEAGLKCIQ GKGIVNSISL KEGEEKFIEQ 480
  481 ATLVKRYGAA AIIMAFDEQG QADTKARKVE ICTRAYRVLV DKVGFPPEDI IFDPNIFAIA 540
  541 TGIDEHDNYA VDFIDAIKEI KATLPHAMIS GGVSNVSFSF RGNNPVREAI HAVFLYHAIK 600
  601 VGMDMGIVNA GQLAIFDDID PELKVRVENV VLNLPCPVEG SNNTEQLLEI AEKFRGDGSS 660
  661 SAKKEDLEWR SWPVNQRLAH ALVKGITEFI DEDTEAARQA ASRPLDVIEG PLMDGMNIVG 720
  721 DLFGSGKMFL PQVVKSARVM KKAVAYLNPF IEKEKVAGQS NGKILMVTVK SDVHDIGKNI 780
  781 VGVVLACNGF EVFDLGVMVS VERILEAVKE HNIDIIGMSG LITPSLDEMV HNVKTFHREG 840
  841 LTIPAIIGGA TCSKIHTAVK IAPHYPHGAI YIADASRAVP MVSKLVNNET RQATIDETYA 900
  901 EYDDMRTKRL SQAKRKEIVS LEAARENRCQ HDWANYSPFK PNVLGRQVFD DYPLTDLVDR 960
  961 IDWTPFFRAW ELHGHYPEIL SDKVVGVEAQ KLFSDGKAML KKIIEEKWLT AKGVIGLFPA1020
 1021 NTVGFDDIEL YTDETRTEVE LTTHHLRMQL ERVGNDNFCL ADFVAPKDSG VADYMGGFAV1080
 1081 TAGHGIDEHV ARFEANHDDY NAIMLKCLAD RLAEAFAERM HERVRKEFWG YAADEQLDNE1140
 1141 ALIREKYKGI RPAPGYPACP DHTEKGLLWE LLKPNETIDL NITESYAMFP TAAVSGWYFA1200
 1201 HPKSRYFGVS NIGRDQVEDY AKRKGMTVAE TEKWLAPVLD YDPE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..619] PSI-BLAST 112.0 Cobalamin-dependent methionine synthase (MetH) from Thermotoga maritima (Oxidized, Monoclinic)
    2 View Details [620..652] PSI-BLAST 49.522879 Methylmalonyl-CoA mutase alpha subunit, domain 1; Methylmalonyl-CoA mutase alpha subunit, C-terminal domain
    3 View Details [653..1244] PSI-BLAST 1000.0 Methionine synthase domain; Methionine synthase, C-terminal domain; Methionine synthase SAM-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • dihydropteroate synthase activity
    		•  5.55484533231129 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  3.53817178180686 bayes_pls_golite062009
  • methyltransferase activity
    		•  3.47355858135695 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.39246539615995 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.30536381024187 bayes_pls_golite062009
  • transferase activity
    		•  2.35234138809715 bayes_pls_golite062009
  • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
    		•  1.59882258515727 bayes_pls_golite062009
  • catalytic activity
    		•  1.41033217274476 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.09502814971491 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.775834109629976 bayes_pls_golite062009
  • binding
    		•  0.660910809839792 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  0.570043482286316 bayes_pls_golite062009
  • protein binding
    		•  0.422094211438801 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.246882532482481 bayes_pls_golite062009
  • methionine synthase activity
    		•  0.191040886553873 bayes_pls_golite062009
  • 5-methyltetrahydrofolate-dependent methyltransferase activity
    		•  0.191040886553873 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle