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Protein Overview: VPS45_YEAST

General Information:
Name(s) found: VPS45_YEAST [Swiss-Prot]
Description(s) found:
  • Vacuolar protein sorting-associated protein 45 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS45 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 577 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLFDVADFY INKIVTSQSK LSVANVNEHQ RIKVLLLDKN TTPTISLCAT QSELLKHEIY  60
   61 LVERIENEQR EVSRHLRCLV YVKPTEETLQ HLLRELRNPR YGEYQIFFSN IVSKSQLERL 120
  121 AESDDLEAVT KVEEIFQDFF ILNQDLFSFD LQPREFLSNK LVWSEGGLTK CTNSLVSVLL 180
  181 SLKIKPDIRY EGASKICERL AKEVSYEIGK NERTFFDFPV MDSTPVLLIL DRNTDPITPL 240
  241 LQPWTYQSMI NEYIGIKRNI VDLSKVPRID KDLEKVTLSS KQDAFFRDTM YLNFGELGDK 300
  301 VKQYVTTYKD KTQTNSQINS IEDIKNFIEK YPEFRKLSGN VAKHMAIVGE LDRQLKIKNI 360
  361 WEISEIEQNL SAHDANEEDF SDLIKLLQNE AVDKYYKLKL ACIYSLNNQT SSDKIRQLVE 420
  421 ILSQQLPPED VNFFHKFKSL FSRQDKMTQS NHDKDDILTE LARRFNSRMN SKSNTAENVY 480
  481 MQHIPEISSL LTDLSKNALF RDRFKEIDTQ GHRVIGNQQS KDIPQDVILF VIGGVTYEEA 540
  541 RLVHDFNGTM NNRMRVVLGG TSILSTKEYM DSIRSAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..136] PSI-BLAST 423.0103 Neuronal Sec1, NSec1
    2 View Details [137..244]
    [484..577]    		 PSI-BLAST 423.0103 Neuronal Sec1, NSec1
    3 View Details [245..356] PSI-BLAST 423.0103 Neuronal Sec1, NSec1
    4 View Details [357..483] PSI-BLAST 423.0103 Neuronal Sec1, NSec1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • SNARE binding
    		•  4.56428593085019 bayes_pls_golite062009
  • syntaxin binding
    		•  3.46044132736061 bayes_pls_golite062009
  • binding
    		•  2.7837022903231 bayes_pls_golite062009
  • protein binding
    		•  2.77285532000616 bayes_pls_golite062009
  • syntaxin-1 binding
    		•  0.269372794919901 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle