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Protein Overview: VHS3_YEAST

General Information:
Name(s) found: VHS3_YEAST [Swiss-Prot]
Description(s) found:
  • Phosphopantothenoylcysteine decarboxylase subunit VHS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VHS3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 674 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNKSSLKNN RKGVASNTLS GAEQANIGSS AMPDTNSTGP FSSVSSLDTP VVRKSTSPTG  60
   61 SQTKSIMNAS GTSGAVVSNT PEPGLKRIPT VTFSDPKLGS LRSDVEQTPP NQVARQSSEK 120
  121 KATSVHIAAE GANQGRNLKD INTKVPKDGE ASASSFSTPT SILSNADMGN NISSLLAKKL 180
  181 SFTGGTDSIL NSDNSSDSPR KEHPHFYVED PLHTPSVRSR SNSTSPRPSV VVNTFNPINI 240
  241 EREGSISKTG EPTLLESVLE EAMSPNAVSN PLKRENIMTN MDPRLPQDDG KLHVLFGATG 300
  301 SLSVFKLKHM IRKLEEIYGR DKICIQVILT NSATKFFAMK YMRKNKKQHN SIDTSFNSTN 360
  361 SNAGNITGNK KKVASLEKFS IQKTSSNSAA SQTNNKQEEE KQMASTTGFP STLGGSRTYS 420
  421 NSSNVVSQHP QIELPAHIQF WTDQDEWDVW RQRTDPVLHI ELRRWADILV VAPLTANTLA 480
  481 KIALGLCDNL LTSVIRAWNP TFPIFLAPSM GSGTFNSIMT KKHFRIIQEE MPWVTVFKPS 540
  541 EKVMGINGDI GLSGMMDANE IVGKIVVKLG GYPDVSAGKE EEEDEDNDEE DDNKKNDTGG 600
  601 KDEDNDDDDD DDDDDDDDDD DDDDDDDDDD DDDDDDDDDD DDDDDDDDDD EDDEDEDEDD 660
  661 EGKKKEDKGG LQRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] deduced N/A No confident structure predictions are available.
    2 View Details [282..375] Pcons 1.88 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a)
    3 View Details [376..592] PSI-BLAST 371.9897 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a)
    4 View Details [593..674] deduced N/A No confident structure predictions are available.
    5 View Details [574..674] PSI-BLAST 4.69897 Strucuture of the C-terminal domain of human thrombospondin-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • phosphopantothenoylcysteine decarboxylase activity
    		•  3.86093811191169 bayes_pls_golite062009
  • phosphopantothenate--cysteine ligase activity
    		•  2.64345867885176 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.79168084682693 bayes_pls_golite062009
  • catalytic activity
    		•  1.51672397362026 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.03827559540394 bayes_pls_golite062009
  • binding
    		•  0.69350040563585 bayes_pls_golite062009
  • protein binding
    		•  0.003958060867923 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle