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Protein Overview: THDH_YEAST

General Information:
Name(s) found: THDH_YEAST [Swiss-Prot]
Description(s) found:
  • Threonine dehydratase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ILV1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATLLKQPL CTVVRQGKQS KVSGLNLLRL KAHLHRQHLS PSLIKLHSEL KLDELQTDNT  60
   61 PDYVRLVLRS SVYDVINESP ISQGVGLSSR LNTNVILKRE DLLPVFSFKL RGAYNMIAKL 120
  121 DDSQRNQGVI ACSAGNHAQG VAFAAKHLKI PATIVMPVCT PSIKYQNVSR LGSQVVLYGN 180
  181 DFDEAKAECA KLAEERGLTN IPPFDHPYVI AGQGTVAMEI LRQVRTANKI GAVFVPVGGG 240
  241 GLIAGIGAYL KRVAPHIKII GVETYDAATL HNSLQRNQRT PLPVVGTFAD GTSVRMIGEE 300
  301 TFRVAQQVVD EVVLVNTDEI CAAVKDIFED TRSIVEPSGA LSVAGMKKYI STVHPEIDHT 360
  361 KNTYVPILSG ANMNFDRLRF VSERAVLGEG KEVFMLVTLP DVPGAFKKMQ KIIHPRSVTE 420
  421 FSYRYNEHRH ESSSEVPKAY IYTSFSVVDR EKEIKQVMQQ LNALGFEAVD ISDNELAKSH 480
  481 GRYLVGGASK VPNERIISFE FPERPGALTR FLGGLSDSWN LTLFHYRNHG ADIGKVLAGI 540
  541 SVPPRENLTF QKFLEDLGYT YHDETDNTVY QKFLKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77]
    [103..212]    		 PSI-BLAST 1441.0 Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain
    2 View Details [78..102]
    [213..386]    		 PSI-BLAST 1441.0 Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain
    3 View Details [387..576] PSI-BLAST 1441.0 Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetolactate synthase activity
    		•  6.50887202511626 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  5.28856942236052 bayes_pls_golite062009
  • threonine racemase activity
    		•  4.44340924206787 bayes_pls_golite062009
  • threonine synthase activity
    		•  3.59927532963055 bayes_pls_golite062009
  • cysteine synthase activity
    		•  3.57860549303214 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  3.33109959091277 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.99526226543975 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • binding
    		•  1.14906798355281 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • catalytic activity
    		•  0.645256181736122 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • protein binding
    		•  0.341967829237094 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.248470717905239 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle