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Protein Overview: SRB8_YEAST

General Information:
Name(s) found: SRB8_YEAST [Swiss-Prot]
Description(s) found:
  • Mediator of RNA polymerase II transcription subunit 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRB8 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1427 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNGSGRYLL TPPDDLHPYV PSSKPQEQVY PDFKPWEHTA AEDQILANFV AKGFYHTPMV  60
   61 NFESISARSS VHESLVTQSN ILSQQFDKII KIREDHINKI PSNSTTTLHG PGFQLPNRIT 120
  121 LTDHRKETWL HELSSSHTSL VKIGKFIPHG LKRRQVIEQC YLKFIPLKRA IWLIKCCYFI 180
  181 EWKSNHKKKR SNAAGADDAI SMHLLKDWTD TFVYILEKLI FDMTNHYNDS QQLRTWKRQI 240
  241 SYFLKLLGNC YSLRLINKEI FHHWLVEFIN KMENFEFLPL SLHILMIFWN DICQIDTNAP 300
  301 VAATITSSQK EPFFLVTKIT DMLLHKYYIV SSSKSMINDE NYIINDIKKN NKIKLNILKI 360
  361 LSSLILKIFQ EQSLEVFIFP TSNWEIYKPL LFEIVSNADT NQNSDMKKKL ELISYRNESL 420
  421 KNNSSIRNVI MSASNANDFQ LTIVTCKQFP KLSCIQLNCI DTQFTKLLDD NPTEFDWPTY 480
  481 VDQNPLTMHK IIQLILWSIH PSRQFDHYES NQLVAKLLLL RINSTDEDLH EFQIEDAIWS 540
  541 LVFQLAKNFS AQKRVVSYMM PSLYRLLNIL ITYGIIKVPT YIRKLISSGL LYLQDSNDKF 600
  601 VHVQLLINLK ISPLMKSQYN MVLRNVMEYD VKFYEIFNFD QLVEITEQIK MRILSNDITN 660
  661 LQLSKTPLSI KIMVAEWYLS HLCSGILSSV NRTVLLKIFK IFCIDLEVFH HFFKWIEFIV 720
  721 YHQLLSDIES LEALMDILLC YQKLFSQFIN DHILFTKTFI FIYKKVLKEK DVPAYNVTSF 780
  781 MPFWKFFMKN FPFVLKVDND LRIELQSVYN DEKLKTEKLK NDKSEVLKVY SMINNSNQAV 840
  841 GQTWNFPEVF QVNIRFLLHN SEIIDTNTSK QFQKARNNVM LLIATNLKEY NKFMSIFLKR 900
  901 KDFTNKNLIQ LISLKLLTFE VTQNVLGLEY IIRLLPINLE NNDGSYGLFL KYHKEQFIKS 960
  961 NFEKILLTCY ELEKKYHGNE CEINYYEILL KILITYGSSP KLLATSTKII MLLLNDSVEN1020
 1021 SSNILEDILY YSTCPSETDL NDIPLGSGQP DNDTVVTNDD KSDDDDHTVD EIDHVEYYVM1080
 1081 MDFANLWVFQ AFTCFCIKKI MENNEPAMAM EDLKNFIFQI IEITNSNDLC SQIFDQLKDM1140
 1141 QTIEMITQIV EKDFCTSCLQ NNNQKIDDNY IVVVIEIITS LSMRFQRETS GMIVISMENY1200
 1201 HLLIKIIRQL SELNEGNLSK REIQIDAVLK IFSFHQDSIF QRIIADLSAD KPTSPFIDSI1260
 1261 CKLFDKISFN LRLKLFLYEI LSSLKSFAIY SSTIDAPAFH TSGKVELPKK LLNLPPFQVS1320
 1321 SFVKETKLHS GDYGEEEDAD QEESFSLNLG IGIVEIAHEN EQKWLIYDKK DHKYVCTFSM1380
 1381 EPYHFISNYN TKYTDDMATG SNDTTAFNDS CVNLSLFDAR FERKNPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..340] MSA 4.012926 View MSA. No confident structure predictions are available.
    2 View Details [341..665] deduced N/A No confident structure predictions are available.
    3 View Details [666..1059] MSA 1.003 View MSA. No confident structure predictions are available.
    4 View Details [1060..1427] deduced N/A No confident structure predictions are available.
    5 View Details [548..637] deduced N/A No confident structure predictions are available.
    6 View Details [638..845] deduced N/A No confident structure predictions are available.
    7 View Details [846..1058] deduced N/A No confident structure predictions are available.
    8 View Details [1059..1251] deduced N/A No confident structure predictions are available.
    9 View Details [1252..1427] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle