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Protein Overview: PUR91_YEAST

General Information:
Name(s) found: PUR91_YEAST [Swiss-Prot]
Description(s) found:
  • Bifunctional purine biosynthesis protein ADE16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE16 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 591 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKYTKTAIL SVYDKTGLLD LAKGLVENNV RILASGGTAN MVREAGFPVD DVSSITHAPE  60
   61 MLGGRVKTLH PAVHAGILAR NLEGDEKDLK EQHIDKVDFV VCNLYPFKET VAKIGVTVQE 120
  121 AVEEIDIGGV TLLRAAAKNH SRVTILSDPN DYSIFLQDLS KDGEISQDLR NRFALKAFEH 180
  181 TADYDAAISD FFRKQYSEGK AQLPLRYGCN PHQRPAQAYI TQQEELPFKV LCGTPGYINL 240
  241 LDALNSWPLV KELSASLNLP AAASFKHVSP AGAAVGLPLS DVERQVYFVN DMEDLSPLAC 300
  301 AYARARGADR MSSFGDFIAL SNIVDVATAK IISKEVSDGV IAPGYEPEAL NILSKKKNGK 360
  361 YCILQIDPNY VPGQMESREV FGVTLQQKRN DAIINQSTFK EIVSKNKALT EQAVIDLTVA 420
  421 TLVLKYTQSN SVCYAKNGMV VGLGAGQQSR IHCTRLAGDK TDNWWLRQHP KVLNMKWAKG 480
  481 IKRADKSNAI DLFVTGQRIE GPEKVDYESK FEEVPEPFTK EERLEWLSKL NNVSLSSDAF 540
  541 FPFPDNVYRA VQSGVKFITA PSGSVMDKVV FQAADSFDIV YVENPIRLFH H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..197] PSI-BLAST 11000.0 IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC; AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
    2 View Details [198..378] PSI-BLAST 11000.0 IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC; AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
    3 View Details [379..591] PSI-BLAST 11000.0 IMP cyclohydrolase domain of bifunctional purine biosynthesis enzyme ATIC; AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • IMP cyclohydrolase activity
    		•  2.44338227123463 bayes_pls_golite062009
  • phosphoribosylaminoimidazolecarboxamide formyltransferase activity
    		•  2.17104645465987 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  2.1190774640451 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.79965948308471 bayes_pls_golite062009
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  1.51378035087272 bayes_pls_golite062009
  • binding
    		•  1.21541060770936 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  1.19388272840449 bayes_pls_golite062009
  • deaminase activity
    		•  1.16510523659661 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.03324558866637 bayes_pls_golite062009
  • cytidine deaminase activity
    		•  0.870445440530128 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.738911503392967 bayes_pls_golite062009
  • carbon-oxygen lyase activity, acting on phosphates
    		•  0.344740566585736 bayes_pls_golite062009
  • electron carrier activity
    		•  0.178707818321223 bayes_pls_golite062009
  • protein binding
    		•  0.072557222523031 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle