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Protein Overview: PCL8_YEAST

General Information:
Name(s) found: PCL8_YEAST [Swiss-Prot]
Description(s) found:
  • PHO85 cyclin-8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCL8 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 492 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANDQDPNKS LINDALTRSM SEFYDDDDDN DSDMCRANDE GEDVFDLPLK VGVSQSRNFS  60
   61 EVNDVLDPLS SLHGPSKKVR FEQQKQQQQH QQLHNDFNTD FNLKSPSSKK MGVEQLIQSA 120
  121 NEINDYLANN IDKVNSFNSE LLSGSGKLPG RVKSDTATQG TGRLDSMSNF ALSDTELDND 180
  181 DDNYLLDPLA NASSTTPTVE HHGYSLLDKA LSTSDKEKIY TNKVNSNSQI DTDNHSHESG 240
  241 NTTNNETDEN ESSEILDYTK FDSFPYPPSS APNGEPPDLK VLSIECEQEN EKELRRISLL 300
  301 LDHYESIPKI PELSDDEALS KFRENIELIL QLSKKINDNA NTLAISSEDP QKFVNFVMKN 360
  361 PPSLSFRDFI DRIQNKCMFG AVVYLGATYL LQLVFLTRDE MDGPIKLKAK LQEDQAHRII 420
  421 ISTIRIATKL LEDFVHSQNY ICKVFGISKR LLTKLEISFM ASVNFDGLMI TCEKLEKTLH 480
  481 ILDDTRQALG NT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..290] deduced N/A No confident structure predictions are available.
    2 View Details [291..492] MSA 41.076995 View MSA. No confident structure predictions are available.
    3 View Details [309..492] FFAS03 1.39 Viral cyclin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • cyclin-dependent protein kinase regulator activity
    		•  5.12463430024071 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  1.93343502830716 bayes_pls_golite062009
  • binding
    		•  1.73927974260891 bayes_pls_golite062009
  • protein binding
    		•  1.37207701115974 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.31222872955439 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.802637318318368 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.753288291901404 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.713321295552366 bayes_pls_golite062009
  • DNA binding
    		•  0.660292655137288 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.461517963237846 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.290993164406505 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.181080585275576 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle