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Protein Overview: EIF3B_YEAST

General Information:
Name(s) found: EIF3B_YEAST [Swiss-Prot]
Description(s) found:
  • Eukaryotic translation initiation factor 3 subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRT1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNFLPRTLK NIYELYFNNI SVHSIVSRNT QLKRSKIIQM TTETFEDIKL EDIPVDDIDF  60
   61 SDLEEQYKVT EEFNFDQYIV VNGAPVIPSA KVPVLKKALT SLFSKAGKVV NMEFPIDEAT 120
  121 GKTKGFLFVE CGSMNDAKKI IKSFHGKRLD LKHRLFLYTM KDVERYNSDD FDTEFREPDM 180
  181 PTFVPSSSLK SWLMDDKVRD QFVLQDDVKT SVFWNSMFNE EDSLVESREN WSTNYVRFSP 240
  241 KGTYLFSYHQ QGVTAWGGPN FDRLRRFYHP DVRNSSVSPN EKYLVTFSTE PIIVEEDNEF 300
  301 SPFTKKNEGH QLCIWDIASG LLMATFPVIK SPYLKWPLVR WSYNDKYCAR MVGDSLIVHD 360
  361 ATKNFMPLEA KALKPSGIRD FSFAPEGVKL QPFRNGDEPS VLLAYWTPET NNSACTATIA 420
  421 EVPRGRVLKT VNLVQVSNVT LHWQNQAEFL CFNVERHTKS GKTQFSNLQI CRLTERDIPV 480
  481 EKVELKDSVF EFGWEPHGNR FVTISVHEVA DMNYAIPANT IRFYAPETKE KTDVIKRWSL 540
  541 VKEIPKTFAN TVSWSPAGRF VVVGALVGPN MRRSDLQFYD MDYPGEKNIN DNNDVSASLK 600
  601 DVAHPTYSAA TNITWDPSGR YVTAWSSSLK HKVEHGYKIF NIAGNLVKED IIAGFKNFAW 660
  661 RPRPASILSN AERKKVRKNL REWSAQFEEQ DAMEADTAMR DLILHQRELL KQWTEYREKI 720
  721 GQEMEKSMNF KIFDVQPEDA SDDFTTIEEI VEEVLEETKE KVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] PSI-BLAST 16.69897 Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
    2 View Details [161..679] PSI-BLAST 37.522879 Actin interacting protein 1
    3 View Details [680..763] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  4.50438526063124 bayes_pls_golite062009
  • translation initiation factor activity
    		•  3.27900316559423 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.03004688154589 bayes_pls_golite062009
  • mRNA binding
    		•  2.92795844574986 bayes_pls_golite062009
  • binding
    		•  2.80563734517858 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
    		• 1.49431666307335 bayes_pls_golite062009
  • protein binding
    		•  1.02232785292059 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.90573796517364 bayes_pls_golite062009
  • RNA cap binding
    		•  0.847034036194541 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.32812362201346 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
    2
    Term Confidence Notes
  • structural molecule activity
    		•  2.6914565031145 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.29806492548141 bayes_pls_golite062009
  • binding
    		•  1.58733371663063 bayes_pls_golite062009
  • RNA binding
    		•  1.54614730254863 bayes_pls_golite062009
    		• 1.53488375271101 bayes_pls_golite062009
  • protein binding
    		•  1.11897341394404 bayes_pls_golite062009
  • snoRNA binding
    		•  0.503568445551651 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.417970425588631 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle