YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: ARO1_YEAST

General Information:
Name(s) found: ARO1_YEAST [Swiss-Prot]
Description(s) found:
  • Pentafunctional AROM polypeptide OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARO1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1588 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQLAKVPIL GNDIIHVGYN IHDHLVETII KHCPSSTYVI CNDTNLSKVP YYQQLVLEFK  60
   61 ASLPEGSRLL TYVVKPGETS KSRETKAQLE DYLLVEGCTR DTVMVAIGGG VIGDMIGFVA 120
  121 STFMRGVRVV QVPTSLLAMV DSSIGGKTAI DTPLGKNFIG AFWQPKFVLV DIKWLETLAK 180
  181 REFINGMAEV IKTACIWNAD EFTRLESNAS LFLNVVNGAK NVKVTNQLTN EIDEISNTDI 240
  241 EAMLDHTYKL VLESIKVKAE VVSSDERESS LRNLLNFGHS IGHAYEAILT PQALHGECVS 300
  301 IGMVKEAELS RYFGILSPTQ VARLSKILVA YGLPVSPDEK WFKELTLHKK TPLDILLKKM 360
  361 SIDKKNEGSK KKVVILESIG KCYGDSAQFV SDEDLRFILT DETLVYPFKD IPADQQKVVI 420
  421 PPGSKSISNR ALILAALGEG QCKIKNLLHS DDTKHMLTAV HELKGATISW EDNGETVVVE 480
  481 GHGGSTLSAC ADPLYLGNAG TASRFLTSLA ALVNSTSSQK YIVLTGNARM QQRPIAPLVD 540
  541 SLRANGTKIE YLNNEGSLPI KVYTDSVFKG GRIELAATVS SQYVSSILMC APYAEEPVTL 600
  601 ALVGGKPISK LYVDMTIKMM EKFGINVETS TTEPYTYYIP KGHYINPSEY VIESDASSAT 660
  661 YPLAFAAMTG TTVTVPNIGF ESLQGDARFA RDVLKPMGCK ITQTATSTTV SGPPVGTLKP 720
  721 LKHVDMEPMT DAFLTACVVA AISHDSDPNS ANTTTIEGIA NQRVKECNRI LAMATELAKF 780
  781 GVKTTELPDG IQVHGLNSIK DLKVPSDSSG PVGVCTYDDH RVAMSFSLLA GMVNSQNERD 840
  841 EVANPVRILE RHCTGKTWPG WWDVLHSELG AKLDGAEPLE CTSKKNSKKS VVIIGMRAAG 900
  901 KTTISKWCAS ALGYKLVDLD ELFEQQHNNQ SVKQFVVENG WEKFREEETR IFKEVIQNYG 960
  961 DDGYVFSTGG GIVESAESRK ALKDFASSGG YVLHLHRDIE ETIVFLQSDP SRPAYVEEIR1020
 1021 EVWNRREGWY KECSNFSFFA PHCSAEAEFQ ALRRSFSKYI ATITGVREIE IPSGRSAFVC1080
 1081 LTFDDLTEQT ENLTPICYGC EAVEVRVDHL ANYSADFVSK QLSILRKATD SIPIIFTVRT1140
 1141 MKQGGNFPDE EFKTLRELYD IALKNGVEFL DLELTLPTDI QYEVINKRGN TKIIGSHHDF1200
 1201 QGLYSWDDAE WENRFNQALT LDVDVVKFVG TAVNFEDNLR LEHFRDTHKN KPLIAVNMTS1260
 1261 KGSISRVLNN VLTPVTSDLL PNSAAPGQLT VAQINKMYTS MGGIEPKELF VVGKPIGHSR1320
 1321 SPILHNTGYE ILGLPHKFDK FETESAQLVK EKLLDGNKNF GGAAVTIPLK LDIMQYMDEL1380
 1381 TDAAKVIGAV NTVIPLGNKK FKGDNTDWLG IRNALINNGV PEYVGHTAGL VIGAGGTSRA1440
 1441 ALYALHSLGC KKIFIINRTT SKLKPLIESL PSEFNIIGIE STKSIEEIKE HVGVAVSCVP1500
 1501 ADKPLDDELL SKLERFLVKG AHAAFVPTLL EAAYKPSVTP VMTISQDKYQ WHVVPGSQML1560
 1561 VHQGVAQFEK WTGFKGPFKA IFDAVTKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] PSI-BLAST 1193.0 Dehydroquinate synthase, DHQS
    2 View Details [178..188]
    [204..267]    		 PSI-BLAST 1193.0 Dehydroquinate synthase, DHQS
    3 View Details [189..203]
    [268..401]    		 PSI-BLAST 1193.0 Dehydroquinate synthase, DHQS
    4 View Details [402..423]
    [654..715]
    [854..880]    		 PSI-BLAST 788.9897 No description for 1ln5A_ was found.
    5 View Details [424..653]
    [716..853]    		 PSI-BLAST 788.9897 No description for 1ln5A_ was found.
    6 View Details [881..1057] PSI-BLAST 166.69897 Shikimate kinase (AroK)
    7 View Details [1058..1070]
    [1196..1304]    		 PSI-BLAST 149.07631 Type I 3-dehydroquinate dehydratase
    8 View Details [1071..1195] PSI-BLAST 149.07631 Type I 3-dehydroquinate dehydratase
    9 View Details [1305..1420] Pfam 5.30103 Shikimate / quinate 5-dehydrogenase No confident structure predictions are available.
    10 View Details [1421..1588] PSI-BLAST 8.221849 Glutamyl tRNA-reductase dimerization domain; Glutamyl tRNA-reductase middle domain; Glutamyl tRNA-reductase catalytic, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-dehydroquinate synthase activity
    		•  2.66599995323323 bayes_pls_golite062009
  • catalytic activity
    		•  2.37357608468991 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.67555894260491 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.60362129760665 bayes_pls_golite062009
  • carbon-oxygen lyase activity, acting on phosphates
    		•  1.17319455535469 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.9498376010104 bayes_pls_golite062009
  • binding
    		•  0.269295154787597 bayes_pls_golite062009
    2
    Term Confidence Notes
  • 3-phosphoshikimate 1-carboxyvinyltransferase activity
    		•  4.55308689407075 bayes_pls_golite062009
  • catalytic activity
    		•  2.54689525592227 bayes_pls_golite062009
  • transferase activity
    		•  2.40426218246544 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.71244782128226 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  1.33437370519308 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.504749089115909 bayes_pls_golite062009
  • nucleotide binding
    		•  0.0579200404644161 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.0495693457499699 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0346567694159108 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0345962863831976 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle