Protein Overview: APJ1_YEAST

General Information:
Name(s) found:	APJ1_YEAST [Swiss-Prot]
Description(s) found:	J domain-containing protein APJ1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APJ1 PE=1 SV=1 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	528 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQNTSLYDS LNVTAAASTS EIKKAYRNAA LKYHPDKNNH TEESKRKFQE ICQAYEILKD  60
   61 NRLRALYDQY GTTDEVLIQE QQAQAQRQQA GPFSSSSNFD TEAMSFPDLS PGDLFAQFFN 120
  121 SSATPSSNGS KSSFNFSFNN SSTPSFSFVN GSGVNNLYSS SAKYNSNDED HHLDRGPDIK 180
  181 HNLKCTLKEL YMGKTAKLGL NRTRICSVCD GHGGLKKCTC KTCKGQGIQT QTRRMGPLVQ 240
  241 SWSQTCADCG GAGVFVKNKD ICQQCQGLGF IKERKILQVT VQPGSCHNQL IVLTGEGDEV 300
  301 ISTKGGGHEK VIPGDVVITI LRLKDPNFQV INYSNLICKK CKIDFMTSLC GGVVYIEGHP 360
  361 SGKLIKLDII PGEILKPGCF KTVEDMGMPK FINGVRSGFG HLYVKFDVTY PERLEPENAK 420
  421 KIQNILANDK YIKAERSTME TADSDCYCDL EKSYDSVEEH VLSSFEAPNL NNEVIEDDDL 480
  481 GDLINERDSR KRNNRRFDES NINNNNETKR NKYSSPVSGF YDHDINGY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..129]	PSI-BLAST	159.855515	DnaJ chaperone, N-terminal (J) domain
2	View Details	[130..259]	PSI-BLAST	56.0103	Cysteine-rich domain of the chaperone protein DnaJ.
3	View Details	[260..457]	PSI-BLAST	20.522879	Heat shock protein 40 Sis1
4	View Details	[458..528]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
binding	2.63138872417193	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
transcription regulator activity	1.91297632253219	bayes_pls_golite062009
nucleic acid binding	1.6342534817623	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
protein binding	1.60937254813642	bayes_pls_golite062009
DNA binding	1.55234338199368	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

2

Term	Confidence	Notes
binding	2.7298921704023	bayes_pls_golite062009
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
protein binding	1.57926302986794	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle