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Protein Overview: SSDH_ARATH

General Information:
Name(s) found: SSDH_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|6684442|gb|AAF23590.1|AF117335_1 succinic semialdehyde dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|16226915|gb|AAL16297.1|AF428367_1 At1g79440/T8K14_14 [Arabidopsis thaliana] [NCBI NR]
  • gi|15810165|gb|AAL07226.1| putative succinic semialdehyde dehydrogenase gabD [Arabidopsis thaliana] [NCBI NR]
  • gi|15219379|ref|NP_178062.1| ALDH5F1; 3-chloroallyl aldehyde dehydrogenase/ NAD or NADH binding / succinate-semialdehyde dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|118575126|sp|Q9SAK4.2|SSDH_ARATH RecName: Full=Succinate-semialdehyde dehydrogenase, mitochondrial; Short=At-SSADH1; AltName: Full=NAD(+)-dependent succinic semialdehyde dehydrogenase; AltName: Full=Aldehyde dehydrogenase family 5 member F1; Flags: Pre [NCBI NR]
  • Succinate-semialdehyde dehydrogenase, mitochondrial OS=Arabidopsis thaliana GN=ALDH5F1 PE=1 SV=2 [Swiss-Prot]
  • succinic semialdehyde dehydrogenase [Arabidopsis thaliana]gi|15810165|gb|AAL07226.1| putative succinic semialdehyde dehydrogenase gabD [Arabidopsis thaliana]gi|16226915|gb|AAL16297.1| At1g79440/T8K14_14 [Arabidopsis thaliana]gi|15219379|ref|NP_178062.1 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Succinate-semialdehyde dehydrogenase (SSADH1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: SSADH1, SSADH, ALDH5F1 | ALDH5F1 (SUCCINIC SEMIALDEHYDE DEHYDROGENASE); 3-chloroallyl aldehyde dehydrogenase/ succinate-semialdehyde dehydrogenase | chr1:29887418-29892168 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • ALDH5F1 (SUCCINIC SEMIALDEHYDE DEHYDROGENASE); aldehyde dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative succinic semialdehyde dehydrogenase gabD [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • succinic semialdehyde dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g79440/T8K14_14 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ALDH5F1, SSADH1, SSADH | aldehyde dehydrogenase 5F1 | chr1:29882525-29887275 REVERSE LENGTH=528 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    mitochondrial matrix [IDA]
    mitochondrion [IDA]
    Biological Process: response to heat [IMP]
    oxygen and reactive oxygen species metabolic process [IMP]
    gamma-aminobutyric acid catabolic process [IDA]
    glutamate decarboxylation to succinate [IDA][IMP]
    response to light stimulus [IMP]
    response to stress [IMP]
    Molecular Function: succinate-semialdehyde dehydrogenase activity [IDA][ISS]
    3-chloroallyl aldehyde dehydrogenase activity [ISS]
    copper ion binding [IDA]
    NAD or NADH binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIGAAARVA IGGCRKLISS HTSLLLVSSQ CRQMSMDAQS VSEKLRSSGL LRTQGLIGGK  60
   61 WLDSYDNKTI KVNNPATGEI IADVACMGTK ETNDAIASSY EAFTSWSRLT AGERSKVLRR 120
  121 WYDLLIAHKE ELGQLITLEQ GKPLKEAIGE VAYGASFIEY YAEEAKRVYG DIIPPNLSDR 180
  181 RLLVLKQPVG VVGAITPWNF PLAMITRKVG PALASGCTVV VKPSELTPLT ALAAAELALQ 240
  241 AGVPPGALNV VMGNAPEIGD ALLTSPQVRK ITFTGSTAVG KKLMAAAAPT VKKVSLELGG 300
  301 NAPSIVFDDA DLDVAVKGTL AAKFRNSGQT CVCANRVLVQ DGIYDKFAEA FSEAVQKLEV 360
  361 GDGFRDGTTQ GPLINDAAVQ KVETFVQDAV SKGAKIIIGG KRHSLGMTFY EPTVIRDVSD 420
  421 NMIMSKEEIF GPVAPLIRFK TEEDAIRIAN DTIAGLAAYI FTNSVQRSWR VFEALEYGLV 480
  481 GVNEGLISTE VAPFGGVKQS GLGREGSKYG MDEYLEIKYV CLGDMNRH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..528] PSI-BLAST 177.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  4.35175408702761 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  4.2273960318884 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  2.78416888468693 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • acyl-CoA binding
    		•  2.26220696569489 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • retinoid binding
    		•  0.983782635681687 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.900374761028287 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle