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Protein Overview: SGT1_YEAST

General Information:
Name(s) found: SGT1_YEAST [Swiss-Prot]
Description(s) found:
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  • Protein SGT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SGT1 PE=1 SV=1 [Swiss-Prot]
  • Cochaperone protein; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex; acts as a linker between Skp1p and HSP90 complexes [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 395 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVEKDLKTA YKALYDEKEP LKALHLYDEI LKGSPTNLTA LIFKAACLEK LYFGFSDWHS  60
   61 DATMENAKEL LDKALMTAEG RGDRSKIGLV NFRYFVHFFN IKDYELAQSY FKKAKNLGYV 120
  121 DDTLPLWEDR LETKLNKKNK KQKDSTNKHT IKPVESIENR GDNNSSHSPI SPLKIETAPQ 180
  181 ESPKFKIDWY QSSTSVTISL FTVNLPESKE QVNIYISPND RRTLSISYQV PKSGSEFQYN 240
  241 AKLSHEVDPK AVSLKIFPKK LEITLSKIDS TQWKKLEEDI LTESSRLSDE GKNSDSATRL 300
  301 LSAETASKER LSYPSSSKKK IDWSKLDIDE EADEEAGSAD SFFQKLYAGA DPDTKRAMMK 360
  361 SFIESNGTAL STDWEDVSKG TVKTSPPEGM EPKHW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..54] PSI-BLAST 22.221849 Protein phosphatase 5
    2 View Details [55..232] PSI-BLAST 2.045757 Protein farnesyltransferase alpha-subunit
    3 View Details [233..316] PSI-BLAST 5.30103 No description for 1lg0A_ was found.
    4 View Details [317..395] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  6.63746543212322 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.37753885031863 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.68162115570289 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.89523122092864 bayes_pls_golite062009
  • binding
    		•  2.07985546140154 bayes_pls_golite062009
  • ligase activity
    		•  1.72049482453565 bayes_pls_golite062009
  • protein binding
    		•  1.6279032205159 bayes_pls_golite062009
  • signal sequence binding
    		•  0.0492289984665799 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle