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Protein Overview: MDJ1_YEAST

General Information:
Name(s) found: MDJ1_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • DnaJ homolog 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDJ1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFQQGVLSR CSGVFRHHVG HSRHINNILY RHAIAFASIA PRIPKSSFHT SAIRNNEAFK  60
   61 DPYDTLGLKK SATGAEIKKA YYKLAKKYHP DINKEPDAEK KFHDLQNAYE ILSDETKRQQ 120
  121 YDQFGPAAFG GGGAAGGAGG GSGSPFGSQF HDFSGFTSAG GSPFGGINFE DLFGAAFGGG 180
  181 GRGSGGASRS SSMFRQYRGD PIEIVHKVSF KDAVFGSKNV QLRFSALDPC STCSGTGMKP 240
  241 NTHKVSCSTC HGTGTTVHIR GGFQMMSTCP TCNGEGTMKR PQDNCTKCHG EGVQVNRAKT 300
  301 ITVDLPHGLQ DGDVVRIPGQ GSYPDIAVEA DLKDSVKLSR GDILVRIRVD KDPNFSIKNK 360
  361 YDIWYDKEIP ITTAALGGTV TIPTVEGQKI RIKVAPGTQY NQVISIPNMG VPKTSTIRGD 420
  421 MKVQYKIVVK KPQSLAEKCL WEALADVTND DMAKKTMQPG TAAGTAINEE ILKKQKQEEE 480
  481 KHAKKDDDNT LKRLENFITN TFRKIKGDKK N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] PSI-BLAST 169.0 DnaJ chaperone, N-terminal (J) domain
    2 View Details [181..296] PSI-BLAST 142.64593 Cysteine-rich domain of the chaperone protein DnaJ.
    3 View Details [297..511] PSI-BLAST 22.30103 Heat shock protein 40 Sis1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  3.04403163860617 bayes_pls_golite062009
  • chaperone binding
    		•  2.86745334638583 bayes_pls_golite062009
  • protein binding
    		•  2.65982681685488 bayes_pls_golite062009
  • binding
    		•  2.63138872417193 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.31739509739943 bayes_pls_golite062009
  • heat shock protein binding
    		•  2.17994194200939 bayes_pls_golite062009
  • DNA binding
    		•  1.88444505115207 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73387701301727 bayes_pls_golite062009
  • transporter activity
    		•  1.29863098651348 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.927337691912581 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.812144232432417 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.675735261884317 bayes_pls_golite062009
  • protein transporter activity
    		•  0.599800483479766 bayes_pls_golite062009
  • Hsp70 protein binding
    		•  0.541755903922701 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.130185025729857 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.7298921704023 bayes_pls_golite062009
  • protein binding
    		•  2.6297172985864 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.04158808514315 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.594882036388263 bayes_pls_golite062009
  • receptor binding
    		•  0.395342079633271 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.301226589648736 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  0.290861970307477 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  0.290861970307477 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  0.0964866497718595 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.68

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle