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Protein Overview: RFT1_YEAST

General Information:
Name(s) found: RFT1_YEAST [Swiss-Prot]
Description(s) found:
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  • Oligosaccharide translocation protein RFT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFT1 PE=1 SV=1 [Swiss-Prot]
  • Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKNSQLPS TSEQILERST TGATFLMMGQ LFTKLVTFIL NNLLIRFLSP RIFGITAFLE  60
   61 FIQGTVLFFS RDAIRLSTLR ISDSGNGIID DDDEEEYQET HYKSKVLQTA VNFAYIPFWI 120
  121 GFPLSIGLIA WQYRNINAYF ITLPFFRWSI FLIWLSIIVE LLSEPFFIVN QFMLNYAARS 180
  181 RFESIAVTTG CIVNFIVVYA VQQSRYPMGV VTSDIDKEGI AILAFALGKL AHSITLLACY 240
  241 YWDYLKNFKP KKLFSTRLTK IKTRENNELK KGYPKSTSYF FQNDILQHFK KVYFQLCFKH 300
  301 LLTEGDKLII NSLCTVEEQG IYALLSNYGS LLTRLLFAPI EESLRLFLAR LLSSHNPKNL 360
  361 KLSIEVLVNL TRFYIYLSLM IIVFGPANSS FLLQFLIGSK WSTTSVLDTI RVYCFYIPFL 420
  421 SLNGIFEAFF QSVATGDQIL KHSYFMMAFS GIFLLNSWLL IEKLKLSIEG LILSNIINMV 480
  481 LRILYCGVFL NKFHRELFTD SSFFFNFKDF KTVIIAGSTI CLLDWWFIGY VKNLQQFVVN 540
  541 VLFAMGLLAL ILVKERQTIQ SFINKRAVSN SKDV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..497] MSA 2.010881 View MSA. No confident structure predictions are available.
    2 View Details [498..574] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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