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Protein Overview: PAX8_RAT

General Information:
Name(s) found: PAX8_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Paired box protein Pax-8 OS=Rattus norvegicus GN=Pax8 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 457 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    nucleoplasm [IDA]
    Biological Process: thyroid gland development [UNKNOWN][IEA]
    metanephros development [UNKNOWN][IEA]
    multicellular organismal development [IEA]
    positive regulation of transcription, DNA-dependent [UNKNOWN][ISS]
    cell differentiation [UNKNOWN][IEA]
    regulation of transcription, DNA-dependent [IMP]
    regulation of transcription [IEA]
    positive regulation of transcription from RNA polymerase II promoter [IDA]
    Molecular Function: DNA binding [UNKNOWN][IDA][IEA][IMP][ISS]
    protein binding [UNKNOWN][IPI]
    sequence-specific DNA binding [IDA]
    transcription activator activity [UNKNOWN][IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHNSIRSGH GGLNQLGGAF VNGRPLPEVV RQRIVDLAHQ GVRPCDISRQ LRVSHGCVSK  60
   61 ILGRYYETGS IRPGVIGGSK PKVATPKVVE KIGDYKRQNP TMFAWEIRDR LLAEGVCDND 120
  121 TVPSVSSINR IIRTKVQQPF NLPMDSCVAT KSLSPGHTLI PSSAVTPPES PQSDSLGSTY 180
  181 SINGLLGIAQ PGSDNKRKMD DSDQDSCRLS IDSQSSSSGP RKHLRTDTFG QHHLEPLECP 240
  241 FERQHYPEAY ASPSHTKGEQ GLYPLPLLNS TLDDGKATLT PSNTPLGRNL STHQTYPVVA 300
  301 DPHSPYAIKQ ETPELSSSSS TPSSLSSSAF LDLQQVGSGG PAGASVPPFN AFSHAASVYG 360
  361 QFTGQALLSG REMVGPTLPG YPPHIPTSGQ GSYASSAIAG MVAGSEYSGN AYSHTPYASY 420
  421 SEAWRFPNSS LLSSPYYYSS TTRPSAPPTS ATAFDHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle