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Protein Overview: EG11198

General Information:
Name(s) found: glmU / EG11198 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • fused N-acetyl glucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyl transferase / Bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridylyltransferase, hexameric [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 456 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][IEA]
    Biological Process: regulation of cell shape [IEA]
    cell morphogenesis [IEA]
    peptidoglycan biosynthetic process [IEA]
    cellular cell wall organization [IEA]
    lipopolysaccharide biosynthetic process [IEA]
    UDP-N-acetylglucosamine biosynthetic process [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    protein binding [IPILink to PubMed article]
    UDP-N-acetylglucosamine diphosphorylase activity [IDALink to PubMed article][IEA]
    metal ion binding [IEA]
    glucosamine-1-phosphate N-acetyltransferase activity [IDALink to PubMed article][IEA]
    cobalt ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNNAMSVVI LAAGKGTRMY SDLPKVLHTL AGKAMVQHVI DAANELGAAH VHLVYGHGGD  60
   61 LLKQALKDDN LNWVLQAEQL GTGHAMQQAA PFFADDEDIL MLYGDVPLIS VETLQRLRDA 120
  121 KPQGGIGLLT VKLDDPTGYG RITRENGKVT GIVEHKDATD EQRQIQEINT GILIANGADM 180
  181 KRWLAKLTNN NAQGEYYITD IIALAYQEGR EIVAVHPQRL SEVEGVNNRL QLSRLERVYQ 240
  241 SEQAEKLLLA GVMLRDPARF DLRGTLTHGR DVEIDTNVII EGNVTLGHRV KIGTGCVIKN 300
  301 SVIGDDCEIS PYTVVEDANL AAACTIGPFA RLRPGAELLE GAHVGNFVEM KKARLGKGSK 360
  361 AGHLTYLGDA EIGDNVNIGA GTITCNYDGA NKFKTIIGDD VFVGSDTQLV APVTVGKGAT 420
  421 IAAGTTVTRN VGENALAISR VPQTQKEGWR RPVKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..456] PSI-BLAST 96.045757 N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
    		•  4.85526297527966 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  4.84577168407664 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  2.78377598963895 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.55498472336996 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.14294822366154 bayes_pls_golite062009
  • UTP:glucose-1-phosphate uridylyltransferase activity
    		•  2.04683358427931 bayes_pls_golite062009
  • UTP-monosaccharide-1-phosphate uridylyltransferase activity
    		•  1.90086040617591 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • transferase activity
    		•  1.47184463413038 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.17054423506287 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  1.09519444695756 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.983416157001861 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.897978517422275 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  0.857216989692536 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.64885729959093 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.521566400238457 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.66

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle