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Protein Overview: EG10178

General Information:
Name(s) found: cyoA / EG10178 [EcoGene]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • cytochrome o ubiquinol oxidase subunit II / Cytochrome o oxidase subunit II, lipoprotein; also called cytochrome bo(3) ubiquinol oxidase subunit II [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 315 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    respiratory chain [IEA]
    plasma membrane [IEA]
    Biological Process: respiratory electron transport chain [IEA]
    oxidation reduction [IEA]
    electron transport chain [IEA]
    aerobic respiration [IMPLink to PubMed article]
    transport [IEA]
    Molecular Function: cytochrome-c oxidase activity [IEA]
    oxidoreduction-driven active transmembrane transporter activity [IDALink to PubMed article]
    copper ion binding [IEA]
    hydrogen ion transmembrane transporter activity [IDALink to PubMed article]
    cytochrome bo3 ubiquinol oxidase activity [IDALink to PubMed article][IEA]
    electron carrier activity [IDALink to PubMed article][IEA]
    binding [IDALink to PubMed article]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLRKYNKSL GWLSLFAGTV LLSGCNSALL DPKGQIGLEQ RSLILTAFGL MLIVVIPAIL  60
   61 MAVGFAWKYR ASNKDAKYSP NWSHSNKVEA VVWTVPILII IFLAVLTWKT THALEPSKPL 120
  121 AHDEKPITIE VVSMDWKWFF IYPEQGIATV NEIAFPANTP VYFKVTSNSV MNSFFIPRLG 180
  181 SQIYAMAGMQ TRLHLIANEP GTYDGISASY SGPGFSGMKF KAIATPDRAA FDQWVAKAKQ 240
  241 SPNTMSDMAA FEKLAAPSEY NQVEYFSNVK PDLFADVINK FMAHGKSMDM TQPEGEHSAH 300
  301 EGMEGMDMSH AESAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] PSI-BLAST 78.69897 Quinol oxidase (CyoA); Cytochrome O ubiquinol oxidase, subunit II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
    		•  5.5320936660461 bayes_pls_golite062009
  • cytochrome o ubiquinol oxidase activity
    		•  4.09398657845645 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.23507475399426 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.08796639820421 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.79748960625238 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.54465068228515 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  2.52421129381183 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.33710247671877 bayes_pls_golite062009
  • cytochrome-c oxidase activity
    		•  2.27561648237334 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  2.27561648237334 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  2.27561648237334 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  2.21664917825138 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.40469867187886 bayes_pls_golite062009
  • catalytic activity
    		•  0.363071622766357 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle