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Protein Overview: EG10733

General Information:
Name(s) found: phoR / EG10733 [EcoGene]
Description(s) found:
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  • sensory histidine kinase in two-component regulatory system with PhoB / Sensor histidine kinase/phosphatase for pho regulon; cognate to phoB [EcoGene]
  • sensory histidine kinase in two-component regulatory system with PhoB [Escherichia coli K12] [nr-271106-contam.fasta]
  • phosphate regulon sensor protein phoR [Escherichia coli] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • sensory histidine kinase in two-component regulatory system with PhoB [Escherichia coli str. K-12 substr. MG1655] [Ecoli-contam-Dam1-Mind-COMA-MBP-110.fasta]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 431 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    plasma membrane [IEA]
    Biological Process: phosphate transport [IEA]
    signal transduction [IEA]
    two-component signal transduction system (phosphorelay) [IEA]
    regulation of transcription, DNA-dependent [IEA]
    phosphorylation [IEA]
    transport [IEA]
    peptidyl-histidine phosphorylation [IEA]
    Molecular Function: nucleotide binding [IEA]
    two-component sensor activity [IEA]
    ATP binding [IEA]
    protein binding [IEA][IPILink to PubMed article]
    transferase activity, transferring phosphorus-containing groups [IEA]
    transferase activity [IEA]
    kinase activity [IEA]
    signal transducer activity [IEA]
    protein histidine kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLERLSWKRL VLELLLCCLP AFILGAFFGY LPWFLLASVT GLLIWHFWNL LRLSWWLWVD  60
   61 RSMTPPPGRG SWEPLLYGLH QMQLRNKKRR RELGNLIKRF RSGAESLPDA VVLTTEEGGI 120
  121 FWCNGLAQQI LGLRWPEDNG QNILNLLRYP EFTQYLKTRD FSRPLNLVLN TGRHLEIRVM 180
  181 PYTHKQLLMV ARDVTQMHQL EGARRNFFAN VSHELRTPLT VLQGYLEMMN EQPLEGAVRE 240
  241 KALHTMREQT QRMEGLVKQL LTLSKIEAAP THLLNEKVDV PMMLRVVERE AQTLSQKKQT 300
  301 FTFEIDNGLK VSGNEDQLRS AISNLVYNAV NHTPEGTHIT VRWQRVPHGA EFSVEDNGPG 360
  361 IAPEHIPRLT ERFYRVDKAR SRQTGGSGLG LAIVKHAVNH HESRLNIEST VGKGTRFSFV 420
  421 IPERLIAKNS D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [71..183] PSI-BLAST 4.0 Histidine kinase FixL heme domain
    3 View Details [184..431] PSI-BLAST 52.522879 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle